Complement Activation In Malaria Immunity And Pathogenesis

December 21, 2018|
Complement Activation In Malaria Immunity And Pathogenesis by José A. Stoute
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Plasmodium falciparummalaria is responsible for the deaths of nearly 500,000 people each year. Much attention has been paid to antibody and cellular mechanisms of immunity against this pathogen. By contrast, the role that the complement system plays in immunity and pathogenesis in this infection is not very well recognized or understood. Based on the work of a number of research groups, we know that complement plays an important role in these processes. In this book, some of the leading scientists in the field discuss the mechanisms of complement activation during malaria infection as well as the role of complement in the pathogenesis of key syndromes such as severe malarial anemia, cerebral malaria, and placental malaria. In addition, they review recently-identified complement evasion strategies ofP. falciparummerozoites, and how these mechanisms may translate into paradoxical enhancement of infection rather than protection. Finally, they also discuss the role of the mosquito complement system on immunity against the parasite. 

José A. Stoute, M.D.Professor of Medicine, and Microbiology & ImmunologyThe Pennsylvania State University Hershey Medical Center and College of Medicine
Title:Complement Activation In Malaria Immunity And PathogenesisFormat:PaperbackProduct dimensions:149 pages, 9.25 X 6.1 X 0 inShipping dimensions:149 pages, 9.25 X 6.1 X 0 inPublished:December 21, 2018Publisher:Springer International PublishingLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:3030084124

ISBN - 13:9783030084127

Appropriate for ages: All ages

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