Control of Biofilm Infections by Signal Manipulation by J.W. CostertonControl of Biofilm Infections by Signal Manipulation by J.W. Costerton

Control of Biofilm Infections by Signal Manipulation

Foreword byJ.W. CostertonEditorNaomi Balaban

Hardcover | December 17, 2007

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The number of patients affected by and dying from what can be considered as a "biofilm disease" is higher than heart disease and cancer combined. Thus, this is a hugely important work that describes the molecular mechanisms of cell-to-cell communication among bacterial cells in a biofilm, the development of antibiofilm inhibitors such as quorum-sensing inhibitors, and the use of biofilm inhibitors to prevent and treat bacterial infections in humans and other animals.
Title:Control of Biofilm Infections by Signal ManipulationFormat:HardcoverDimensions:191 pages, 9.25 × 6.1 × 0 inPublished:December 17, 2007Publisher:Springer Berlin HeidelbergLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:3540738525

ISBN - 13:9783540738527

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Table of Contents

Introduction.- Bacterial Cell-to-Cell Communication (Quorum Sensing).- Detection in Vitro of Quorum-Sensing Molecules and Their Inhibitors.- Quorum-Sensing Inhibitory Compounds.- Mathematical Modeling of Quorum-Sensing Control in Biofilms.- Animal Models Commonly Used to Study Quorum-Sensing Inhibitors.- In Vivo Studies: Inhibiting Biofilm-Associated Bacterial Infections Using QSIs.- Quorum Sensing in Streptococci.- Ironing Out the Biofilm Problem: The Role of Iron in Biofilm Formation.- Clinical Wound Healing Using Signal Inhibitors.