Controversies In Diabetic Neuropathy

Hardcover | April 27, 2016

byNigel CalcuttEditorPaul Fernyhough

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This latest volume in the International Review of Neurobiology series, provides a comprehensive overview of the state-of-the-art research on the topic. It reviews the current knowledge and understanding in the field, presenting a starting point for researchers and practitioners entering the field. Offers a comprehensive overview of state-of-the-art research on diabetic neuropathy Provides personal critiques from experts in each field Provides a running commentary by editors throughout the book Explores a range of topics including mechanisms of nerve damage, neuropathic pain, new therapies, clinical trials, and animal models of diabetic neuropathy

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This latest volume in the International Review of Neurobiology series, provides a comprehensive overview of the state-of-the-art research on the topic. It reviews the current knowledge and understanding in the field, presenting a starting point for researchers and practitioners entering the field. Offers a comprehensive overview of sta...

Nigel Calcutt is Professor of Pathology at the University of California San Diego. Dr. Calcutt took his B.Sc. in Zoology at Nottingham University, England and then a Ph.D. in Physiology and Pharmacology while working in the laboratory of David Tomlinson. He performed post-doctoral research in the Departments of Pharmacology at St. Bart...
Format:HardcoverDimensions:392 pages, 9.41 × 7.24 × 0.98 inPublished:April 27, 2016Publisher:Academic PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0128039159

ISBN - 13:9780128039151

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Table of Contents

Introduction: David Tomlinson (editor of first edition)"Back in my day& ."

Fit the First: Clinical Context

Calcutt and Fernyhough: " An introduction to the history and controversies of clinical trials in diabetic neuropathy"

Pop-Busui : "Neuropathy in the DCCT/EDIC - what was done then and what we would do better now"

Bril:" The perfect clinical trial"

Fit the Second: New Models of Diabetic Neuropathy

Calcutt and Fernyhough: "An Introduction to the history and controversies of animal models of diabetic neuropathy"

Gardiner and Freeman: " Can diabetic neuropathy be modeled in vitro?"

Yorek: "Alternatives to the streptozotocin-diabetic rodent"

Fit the Third: Mechanisms and Therapies

Fernyhough and Calcutt: "An introduction to the history and controversies of the pathogenesis of diabetic neuropathy"

Yagihashi : "Glucotoxic mechanisms and related therapeutic approaches"

Zochodne: "Sensory neurodegeneration in diabetes: beyond glucotoxicity "

Dobrowsky:" Promoting Neuronal Tolerance of Diabetic Stress: Modulating Molecular Chaperones "

Todorovic: "Painful diabetic neuropathy: Prevention or suppression?"

Fit the Fourth: Translating Science into Medicine

Fernyhough and Calcutt: "New Directions in Diabetic Neuropathy: Evolution or Extinction?"

Vinik, Casellini and Névoret: "Alternative Quantitative Tools in the assessment of diabetic peripheral and autonomic neuropathy"

Malik:" Wherefore art thou, O Treatment for Diabetic Neuropathy?"