Controversies In Diabetic Neuropathy by Nigel CalcuttControversies In Diabetic Neuropathy by Nigel Calcutt

Controversies In Diabetic Neuropathy

byNigel CalcuttEditorPaul Fernyhough

Hardcover | April 27, 2016

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This latest volume in theInternational Review of Neurobiologyseries, provides a comprehensive overview of the state-of-the-art research on the topic. It reviews the current knowledge and understanding in the field, presenting a starting point for researchers and practitioners entering the field.



  • Offers a comprehensive overview of state-of-the-art research on diabetic neuropathy
  • Provides personal critiques from experts in each field
  • Provides a running commentary by editors throughout the book
  • Explores a range of topics including mechanisms of nerve damage, neuropathic pain, new therapies, clinical trials, and animal models of diabetic neuropathy
Nigel Calcutt is Professor of Pathology at the University of California San Diego. Dr. Calcutt took his B.Sc. in Zoology at Nottingham University, England and then a Ph.D. in Physiology and Pharmacology while working in the laboratory of David Tomlinson. He performed post-doctoral research in the Departments of Pharmacology at St. Bart...
Title:Controversies In Diabetic NeuropathyFormat:HardcoverDimensions:392 pages, 9.41 × 7.24 × 0.98 inPublished:April 27, 2016Publisher:Academic PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0128039159

ISBN - 13:9780128039151

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Table of Contents

Introduction: David Tomlinson (editor of first edition)"Back in my day& ."

Fit the First: Clinical Context

Calcutt and Fernyhough: " An introduction to the history and controversies of clinical trials in diabetic neuropathy"

Pop-Busui : "Neuropathy in the DCCT/EDIC - what was done then and what we would do better now"

Bril:" The perfect clinical trial"

Fit the Second: New Models of Diabetic Neuropathy

Calcutt and Fernyhough: "An Introduction to the history and controversies of animal models of diabetic neuropathy"

Gardiner and Freeman: " Can diabetic neuropathy be modeled in vitro?"

Yorek: "Alternatives to the streptozotocin-diabetic rodent"

Fit the Third: Mechanisms and Therapies

Fernyhough and Calcutt: "An introduction to the history and controversies of the pathogenesis of diabetic neuropathy"

Yagihashi : "Glucotoxic mechanisms and related therapeutic approaches"

Zochodne: "Sensory neurodegeneration in diabetes: beyond glucotoxicity "

Dobrowsky:" Promoting Neuronal Tolerance of Diabetic Stress: Modulating Molecular Chaperones "

Todorovic: "Painful diabetic neuropathy: Prevention or suppression?"

Fit the Fourth: Translating Science into Medicine

Fernyhough and Calcutt: "New Directions in Diabetic Neuropathy: Evolution or Extinction?"

Vinik, Casellini and Névoret: "Alternative Quantitative Tools in the assessment of diabetic peripheral and autonomic neuropathy"

Malik:" Wherefore art thou, O Treatment for Diabetic Neuropathy?"