Coronavirus Replication and Reverse Genetics by Luis EnjuanesCoronavirus Replication and Reverse Genetics by Luis Enjuanes

Coronavirus Replication and Reverse Genetics

EditorLuis Enjuanes

Paperback | October 19, 2010

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Until the late 1960s, the coronaviruses were not recognized as pathogens responsible for human diseases (common cold). However, in 2003 human coronaviruses (HCoVs) came to worldwide attention with the emergence of the Severe and Acute Respiratory Syndrome (SARS), produced by a coronavirus (SARS-CoV) that infected more than 8000 people, killing about ten percent of them in 32 countries. The increase in research on coronaviruses soon led to the discovery of another human coronavirus (HCoV-NL63) which is prevalent in 7% of hospital patients and has been associated with bronchiolitis and, possibly, conjunctivitis.
Title:Coronavirus Replication and Reverse GeneticsFormat:PaperbackDimensions:268 pages, 9.25 × 6.1 × 0.03 inPublished:October 19, 2010Publisher:Springer Berlin HeidelbergLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:364205997X

ISBN - 13:9783642059971

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Table of Contents

Coronavirus genome structure and replication.- Coronavirus transcription: a perspective.- The coronavirus replicase.- Viral and cellular proteins involved in coronavirus replication.- Coronavirus reverse genetics by targeted RNA recombination.- Coronavirus reverse genetics and development of vectors for gene expression.- Reverse genetics of coronaviruses using vaccinia virus vectors .- Development of mouse hepatitis virus and SARS-CoV infectious cDNA constructs.- Subject index

Editorial Reviews

Aus den Rezensionen:". Das Buch enthält . Informationen über die Genom-Organisation der Coronaviridae . Die einzelnen Kapitel bestechen durch ihre hohe Transparenz, wie auch durch ihre Einheitlichkeit der Gliederung. Insgesamt spannt das Buch mit der Anordnung der Kapitel einen in sich geschlossenen, kohärenten Bogen. Die einzelnen Kapitel sind von herausragenden Wissenschaftlern zu den jeweiligen Thematiken verfasst . Bestechend sind ferner die zumeist sehr ausführlichen und aktuellen Verweise zur Primärliteratur. Zusammenfassend ein top aktuelles Buch, das nur empfohlen werden kann ."(A. Schmidt, in: Der Mikrobiologe, 2007, Vol. 17, Issue 2, S. 56)