Corynebacterium diphtheriae and Related Toxigenic Species: Genomics, Pathogenicity and Applications by Andreas BurkovskiCorynebacterium diphtheriae and Related Toxigenic Species: Genomics, Pathogenicity and Applications by Andreas Burkovski

Corynebacterium diphtheriae and Related Toxigenic Species: Genomics, Pathogenicity and Applications

byAndreas Burkovski

Hardcover | November 18, 2013

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Corynebacterium diphtheriaeis the classical etiological agent of diphtheria and the type strain of the genusCorynebacterium. While diphtheria of the respiratory tract became rare with the introduction of vaccination programs in industrialized countries, even today several thousand cases per year are reported to the World Health Organization. This shows that diphtheria is not completely eradicated and that reservoirs exist. The book summarizes the latest advances made in understandingC. diphtheriaeand the closely related speciesCorynebacterium ulceransandCorynebacterium pseudotuberculosis. Topics addressed are genomics of toxigenic corynebacteria, host-pathogen-interaction, detection, surveillance and treatment as well as application aspects.

Title:Corynebacterium diphtheriae and Related Toxigenic Species: Genomics, Pathogenicity and ApplicationsFormat:HardcoverDimensions:293 pagesPublished:November 18, 2013Publisher:Springer-Verlag/Sci-Tech/TradeLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:9400776233

ISBN - 13:9789400776234

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Table of Contents

1. Diphtheria and its etiological agents

Andreas Burkovski, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany

2.Corynebacterium diphtheriae,Corynebacterium ulceransandCorynebacterium pseudotuberculosis- General aspects

Ana Luíza de Mattos Guaraldi , Raphael Hirata Júnior & Vasco Ariston de Carvalho Azevedo

3. Comparative genomics and pathogenicity islands ofCorynebacterium diphtheriae,Corynebacterium ulcerans, andCorynebacterium pseudotuberculosis

Eva Trost & Andreas Tauch

4. Corynephages: infections of the infectors

Vartul Sangal & Paul A Hoskisson

5. Toxin structure, delivery and action

Basak Varol, Bilge Özerman Edis & Muhammet Bektaş

6. Iron Acquisition and Iron-Dependent Gene Expression inCorynebacterium diphtheriae

Michael P. Schmitt

7. Assembly and Function of Corynebacterium diphtheriae Pili

Melissa E. Reardon and Hung Ton-That

8. Toxigenic corynebacteria: Adhesion, invasion and host response

Lisa Ott & Andreas Burkovski

9. Detection methods for laboratory diagnosis of diphtheria

Anja Berger, Michael Hogardt, Regina Konrad & Andreas Sing

10. Diphtheria Surveillance

Karen S. Wagner, Katherina Zakikhany, Joanne M. White, Gayatri Amirthalingam, Natasha S. Crowcroft & Androulla Efstratiou

11. History of diphtheria vaccine development

Enrico Malito & Rino Rappuoli

12. Antimicrobial susceptibility and treatment

Aleksandra Anna Zasada

13. Sialidases of Corynebacteria and their Biotechnological Applications

14. Molecular Genetic Tools for Research in Corynebacterium diphtheriae

Diana M. Oram

15. Diphtheria toxin based molecules as therapeutic approaches

Ingo Schubert

Editorial Reviews

From the book reviews:"It extensively examines the genomics, pathogenicity, diagnosis, and treatment of these bacteria as well as vaccine development. . an excellent resource for graduate, postdoctoral fellows, and basic scientists in microbiology, molecular genetics, or public health. It also would be a useful introductory tool for infectious disease fellows who are interested in pursuing public health and/or basic science research as part of a physician/scientist training pathway." (Shirley F. Delair, Doody's Book Reviews, August, 2014)