Current Concepts in Autoimmunity and Chronic Inflammation by Andreas RadbruchCurrent Concepts in Autoimmunity and Chronic Inflammation by Andreas Radbruch

Current Concepts in Autoimmunity and Chronic Inflammation

byAndreas RadbruchEditorPeter E. Lipsky

Paperback | February 12, 2010

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The ethiopathologies of autoimmune diseases are complex. A broad variety of cell types and gene products are involved. However, clinical and experimental evidence suggests that the importance of an individual factor changes during the course of the disease. Factors and cell types that induce acute autoreactivity and initiate an autoimmune disease could be distinct from those that drive a chronic course of that disease
Title:Current Concepts in Autoimmunity and Chronic InflammationFormat:PaperbackDimensions:282 pages, 23.5 × 15.5 × 0.07 inPublished:February 12, 2010Publisher:Springer-Verlag/Sci-Tech/TradeLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:364206745X

ISBN - 13:9783642067457

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Table of Contents

The pitfalls of tolerance.- Fritz Melchers and Antonius Rolink: B cell tolerance - how to make it and how to break it.- Hartmut Wekerle: Breaking ignorance - the case of the brain.- Shimon Sakaguchi, Ruka Setoguchi, Haruhiko Yagi, and Takashi Nomura: Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in self-tolerance and autoimmune disease.- Innate and autoimmunity.- Joel F.G. Cohen-Solal, Venkatesh Jeganathan, Christine M. Grimaldi, Elena Peeva and Betty Diamond: Sex hormones and SLE: influencing the fate of autoreactive B cells.- The link between infection and autommunity.- Mike Recher and Karl S. Lang: Innate (over)immunity and adaptive autoimmune disease.- D.J.B. Marks, Nicholas Avrion Mitchison, A.W. Segal, Jochen Sieper: Can unresolved infection precipitate autoimmune disease?.- Sustaining chronic inflammation.- Udo S. Gaipl, Ahmed Sheriff, Sandra Franz, Luis E. Munoz, Reinhard E. Voll, Joachim R. Kalden, and Martin Herrmann: Inefficient clearance of dying cells and autoreactivity.- Alla Skapenko, Peter E. Lipsky, and Hendrik Schulze-Koops: T cell activation as starter and motor of rheumatic inflammation.- Fionula Mary Brennan, Andrew David Foey and Marc Feldmann: The importance of T cell interactions with macrophages in rheumatoid cytokine production.- Thomas Dörner and Peter E Lipsky: Signalling pathways in B cells: Implications for autoimmunity.- Rudolf A. Manz, Katrin Moser, Gerd-Rüdiger Burmester, Andreas Radbruch, and Falk Hiepe: Immunological memory stabilizing autoreactivity.- Genetics and genes.- Martina Johannesson, Malin Hultqvist, Rikard Holmdahl: Genetics of autoimmune diseases - a multistep process.- Susannah Brydges and Daniel Kastner: the systemic autoinflammatory diseases: inborn errors of the innate immune system .- Subject Index