Current Concepts in Drug Metabolism and Toxicology by Gabrielle M. HawksworthCurrent Concepts in Drug Metabolism and Toxicology by Gabrielle M. Hawksworth

Current Concepts in Drug Metabolism and Toxicology

byGabrielle M. Hawksworth, Gabrielle M. Hawksworth

Other | November 27, 2012

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This new volume ofAdvances in Pharmacologyexplores the current concepts in drug metabolism and toxicology. Chapters cover the Keap1-Nrf2 cell defense pathway, animal models of drug-induced idiosyncratic toxicity and the use of human embryonic and induced pluripotent stem cells for modeling metabolism and toxicity. With a variety of chapters and the best authors in the field, the volume is an essential resource for pharmacologists, immunologists and biochemists alike.

  • Explores the current concepts in drug metabolism and toxicology
  • Chapters cover such areas as the Keap1-Nrf2 cell defense pathway, animal models of drug-induced idiosyncratic toxicity and the use of human embryonic and induced pluripotent stem cells for modeling metabolism and toxicity
  • An essential resource for pharmacologists, immunologists and biochemists alike

Details & Specs

Title:Current Concepts in Drug Metabolism and ToxicologyFormat:OtherDimensions:304 pages, 1 × 1 × 1 inPublished:November 27, 2012Publisher:Academic PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0123983592

ISBN - 13:9780123983596

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Table of Contents

  1. Membrane Transporters in Drug Development
  2. The Keap1-Nrf2 Cell Defence Pathway - A Promising Therapeutic Target?
  3. Animal Models of Idiosyncratic Drug Reactions
  4. Genetic Polymorphisms Affecting Drug Metabolism: Recent Advances and Clinical Aspects
  5. Arylamine N-Acetyltransferases - from Drug Metabolism and Pharmacogenetics to Identification of Novel Targets for Pharmacological Intervention
  6. Human Pluripotent Stem Cells for Modelling Toxicity
  7. Disposition of Biologics