Cytokine Molecular Biology: A Practical Approach

Paperback | June 12, 2003

EditorFran Balkwill

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Cytokine Molecular Biology concentrates on molecular biology techniques for the study of cytokines, cytokine receptors, and cytokine driven processes. Updated topics from the previous edition are: the cloning and expressing cytokine genes;; the detection of cytokine mRNA; receptor bindingstudies; the PC-specific phosphslipase C and sphingomylinases. In addition, new topics covered are the purification, sequencing, and synthesis of cytokines; studying cytokine gene polymorphisms; the use of proteomics in cytokine research; and the Jak/STAT and MAPK signalling pathways. Written byexperts in the field, Cytokine Molecular Biology and Cytokine Cellular Biology form a comprehensive and essential guide to cytokine research.

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Cytokine Molecular Biology concentrates on molecular biology techniques for the study of cytokines, cytokine receptors, and cytokine driven processes. Updated topics from the previous edition are: the cloning and expressing cytokine genes;; the detection of cytokine mRNA; receptor bindingstudies; the PC-specific phosphslipase C and sph...

Fran Balkwill is at Biological Therapeutics Laboratory, ICRF.
Format:PaperbackPublished:June 12, 2003Publisher:Oxford University PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0199638578

ISBN - 13:9780199638574

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Table of Contents

Cloning and expression of cytokine genesMethods for studying cytokine gene polymorphismsNorthern analysis, RT-PCR, Rnase protection, cDNA array systems and in situ hybridization detection of cytokine messenger RNAPurification, sequencing and synthesis of cytokines and chemokinesReceptor binding studiesCytokine signallingCytokine receptor signalling pathways: PC-specific phospholipase C and sphingomyelinasesProteome analysis in cytokine researchConditional and fixed cytokine gene modification in transgenic and mutant mice