Cytokines and Chemokines in Infectious Diseases Handbook by Malak KotbCytokines and Chemokines in Infectious Diseases Handbook by Malak Kotb

Cytokines and Chemokines in Infectious Diseases Handbook

EditorMalak Kotb

Paperback | November 19, 2010

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A comprehensive review of what is known about the role of cytokines and chemokines in a variety of human infectious diseases, including gram-negative and -positive infections, listeriosis, mycobacterial infections, lyme arthritis, pneumonia, fungal infections, HIV, leishmaniasis, and sepsis. The authors demonstrate the different cytokine and chemokine production profiles in response to a wide variety of pathogens and the importance of host genetic factors in determining the type and magnitude of responses to a given microorganism. They also critically evaluate the use of cytokines and anticytokines in the treatment of infectious diseases and show how knowledge of cytokine pleiotropic effects, redundancy, and the complexity of the cytokine network has led to better design and better outcomes in cytokine-based therapies for specific infections.

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Title:Cytokines and Chemokines in Infectious Diseases HandbookFormat:PaperbackDimensions:451 pagesPublished:November 19, 2010Publisher:Humana PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:1617372471

ISBN - 13:9781617372476

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Table of Contents

Introduction: Cytokine Biology Relevant to Infectious DiseasesCharles A. DinarelloI. Cytokines in Infectious DiseasesLeptin: Its Role in Immunomodulation and Susceptibility to InfectionGraham LordCytokine Gene Polymorphism and Host Susceptibility to InfectionFrank StüberII. Cytokines in Gram-Negative InfectionsProinflammatory and Anti-Inflammatory Cytokines as Mediators of Gram-Negative SepsisJean-Marc CavaillonHost Response to Pathogenic Bacteria at Mucosal SitesLaurence Arbibe and Philippe SansonettiMacrophage Migration Inhibitory Factor as a Cytokine of Innate ImmunityThierry CalandraIII. Cytokines in Gram-Positive InfectionsCytokine Patterns in Severe Invasive Group A Streptococcal InfectionsAnna Norrby-Teglund and Malak KotbSuperantigens and Bacterial DNA as Cytokine Inducers in Gram-PositiveSepsisKlaus HeegCytokines and Chemokines in ListeriosisMichael S. Rolph and Stefan H. E. KaufmannIV. Cytokines in Mycobacterial InfectionsRegulation of Cytokines and Chemokines Responses in Human Mycobacterium tuberculosis InfectionZahra Toossi and Jerrold J. EllnerCytokines and Chemokines in Protective and Inflammatory Responses to Infection with Nontuberculous MycobacteriaStefan EhlersHuman Interleukin-12-Interferon-g Axis in Protective Immunity to MycobacteriaClaire Fieschi, Stéphanie Dupuis, Capucine Picard, and Jean-Laurent CasanovaRole of Th1 Cytokines in Host Defenses Against Mycobacterium lepraeElizabeth Pereira Sampaio, Milton Ozorio Moraes, M. Cristina Vidal Pessolani, and Euzenir Nunes SarnoV. Cytokines in Other Bacterial InfectionsPossible Role of Molecular Mimicry in Lyme ArthritisAbbie L. Meyer and Brigitte T. HuberCytokine Responses in Patients with PneumoniaPeter Kragsbjerg and Hans HolmbergVI. Cytokines in Fungal InfectionsCytokines and the Host Defense Against Aspergillus fumigatusEmmanuel Roilides, Joanna Filioti, and Cristina Gil-LamaignereCytokines of Innate and Adaptive Immunity to Candida albicansLuigina RomaniVII. Cytokines in Parasitic InfectionsTh1 and Th2 Cytokines in LeishmaniasisFabienne Tacchini-Cottier, Geneviève Milon, and Jacques A. LouisCytokines in the Regulation of Innate and Adaptive Immunity to Toxoplasma gondiiUlrike Wille and Christopher A. HunterVIII. Cytokines in Viral InfectionsViroceptors: Virus-Encoded Receptors for Cytokines and ChemokinesGrant McFaddenChemokines and Chemokine Receptors in HIV InfectionPaolo LussoCytokines in Viral HepatitisMala K. Maini and Antonio BertolettiIX. Cytokines as Therapeutic Agents in Infectious DiseasesInterferon-g in the Treatment of Infectious DiseasesSteven M. Holland and John I. GallinInterleukin-2 for the Treatment of HIV InfectionGuido Poli, Claudio Fortis, Adriano Lazzarin, and Giuseppe TambussiClinical Applications of G-CSF and GM-CSF in the Treatment of Infectious DiseasesKai Hübel, David C. Dale, Richard K. Root, and W. Conrad LilesX. Anticytokine-Based Therapy in Treatment of Infectious DiseasesAnticytokine Therapies in Patients with Severe Sepsis and Septic ShockPierre-Yves Bochud, Michel P. Glauser, and Thierry CalandraIntravenous Immunoglobulin Adjunctive Therapy in Patients with Streptococcal Toxic Shock Syndrome and Necrotizing FasciitisAnna Norrby-Teglund, Donald E. Low, and Malak KotbIndex

Editorial Reviews

"The material in this handbook is compiled in such a way that the handbook acts as an intersection of the disciplines of immunology and infectious diseases. Individuals from disciplines on either side of the fence will find this a useful resource for learning about the interplay of host humeral immunity and various infections...this book will provide a useful resource as well as a guide for those interested in learning more about cytokines and chemokines in infectious disease." -Clinical Infectious Diseases