Cytoskeleton: Signalling and Cell Regulation: A Practical Approach

Paperback | December 16, 1999

EditorKermit Carraway, Coralie Carraway

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This book provides descriptions of experimental methods in research on the cytoskeleton and its relationships to signaling and cell regulation. Thus, it bridges two active and fertile areas of research. The focus is directed particularly towards methods which take advantage of recent advancesin molecular biology, microscopy and immunological assays. A second emphasis is on methods for understanding dynamic changes in cells. A third emphasis is on the formation and turnover of macromolecular and supramolecular complexes, which are so important in driving cell regulation and thebehaviour of cytoskeletal elements. A combination of practical advice and detailed protocols should make this book valuable for both novice and experienced workers in these burgeoning fields.

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From the Publisher

This book provides descriptions of experimental methods in research on the cytoskeleton and its relationships to signaling and cell regulation. Thus, it bridges two active and fertile areas of research. The focus is directed particularly towards methods which take advantage of recent advancesin molecular biology, microscopy and immuno...

Kermit Carraway is at University of Miami. Coralie Carraway is at University of Miami.
Format:PaperbackPublished:December 16, 1999Publisher:Oxford University PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0199637814

ISBN - 13:9780199637812

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Table of Contents

Preface1. Carraway: Introduction: The cytoskeleton in the transduction of signal and regulation of cellular function2. Ampe and Vandekerckhove: Assaying binding and covalent modifications of cytoskeletal proteins3. Karpova and Cooper: Methods to study actin assembly and dynamics in yeast4. Carraway and Carraway: Signaling complexes: Association of signaling proteins with the cytoskeleton5. Ridley and Flinn: Ras-related GTPases and the cytoskeleton6. Fishkind et al: Applications for analysis of contractile functions in dividing and migrating tissue culture cells7. Zeile et al: Video microscopy: Protocols for examining the actin-based motility of Listeria, Shigella, Vaccinia, and Lanthanum-induced endosomes.8. Downing: Structural studies on tubulin and microtubules9. Inada et al: Regulation of Intermediate Filament Dynamics10. Bermano and Hesketh: The study of mRNA-cytoskeleton interactions and mRNA sorting in mammalian cells11. Goldmann et al: Cell shape control and mechanical signaling through the cytoskeletonAppendixIndex

Editorial Reviews

"This book gives modern insight into the techniques used in cellular signalling research and should not go out of date for a least a decade" Cell Biology International