Defending Life: The Nature of Host-Parasite Relations by Elling UlvestadDefending Life: The Nature of Host-Parasite Relations by Elling Ulvestad

Defending Life: The Nature of Host-Parasite Relations

byElling Ulvestad

Paperback | October 19, 2010

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Defending Life discusses the relationship between hosts and parasites. A major contention of the book is that the immune system depends ontologically on the ecosystem in which it is embedded; it would not have the features it has if it was not related in one way or other to parasitic agents and to the host's own cells and tissues. To sustain the argument, life is investigated at all layers - from molecules up through cells, organisms and ecosystems. Together with the inverse course, which goes from ecological contingencies down to gene-expression profiles, the approach facilitates an advanced understanding of immunocompetence as well as its converse, immunoincompetence. The emphasis on analytical abstractions, coherent patterns and generative mechanisms makes possible the distinction between genuine causality and coincidental associations, and thus increases the understanding of why we observe what we observe. The book contains detailed descriptions of the immune system and the microbial world as well as methodological and conceptual clarifications. "The book is highly recommended to those who want to dig into the scientific challenges involved in understanding the complex demands and tasks that nature had bestowed the immune system. "Professor Roland Jonsson The Gade Institute, University of Bergen, Norway.
Title:Defending Life: The Nature of Host-Parasite RelationsFormat:PaperbackDimensions:260 pages, 9.25 × 6.1 × 0.01 inPublished:October 19, 2010Publisher:Springer NetherlandsLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:9048174236

ISBN - 13:9789048174232

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Table of Contents

Introduction Preface1 Tracks of thought1.1 Organismal maintenance1.2 The war metaphor1.3 Metaimmunological musings2 Immunobiology2.1 The received view2.2 The integrated view2.3 The many and the one3 Adaptive plasticity3.1 Totalities of involvement3.2 Equipping the adaptive toolbox3.3 Exemption explained4 Natura naturans4.1 Situating life4.2 Social evolution4.3 Coevolutionary dynamics5 Disabled defences5.1 Failure to perform5.2 The re-enacting of ancient conflicts5.3 Environmental challengesReferencesIndex

Editorial Reviews

From the reviews:"Defending Life is one of the serious efforts to understand the science of immunology theoretically . . This book is not only an important contribution towards understanding the restrictions under which immunology now functions, but it provocatively suggests how the discipline might reorient itself to address more effectively not only the molecular mechanisms of immune reactions, but also their regulations and organization. . a propitious step towards the full adoption of immunology by philosophy of biology as a member in good standing." (Alfred I. Tauber, Perspectives in Biology and Medicine, Vol. 51 (2), 2008)