Diabetes & C-Peptide: Scientific and Clinical Aspects by Anders A.F. SimaDiabetes & C-Peptide: Scientific and Clinical Aspects by Anders A.F. Sima

Diabetes & C-Peptide: Scientific and Clinical Aspects

EditorAnders A.F. Sima

Hardcover | November 3, 2011

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In Diabetes & C-Peptide: Scientific and Clinical Aspects, a renowned group of leading researchers and physicians offers a comprehensive overview of the role of C-Peptide in type 1 diabetes. The book is organized in five sections. An Introductory section provides the background and key features of C-peptide's physiological function and how its deficiency contributes to complications. The second section describes up-to-date information on the biochemical and molecular actions of C-peptide, including membrane binding, interactions with insulin as well as the interaction between C-peptide and zinc and effects on microvascular vasoreactivity. The third section summarizes in vivo animal studies of the type 1 diabetic complications. The fourth section reviews the clinical efforts of C-peptide on inflammation, cardiovascular complication, neuropathy and nephropathy. Finally, in the Conclusions section, a summary of the present state of C-peptide, outstanding questions, and the likely direction of the field are offered. Developed by the foremost investigators in the rapidly moving field of C-peptide research, Diabetes & C-Peptide: Scientific and Clinical Aspects is an important contribution to the literature for all researchers and physicians concerned about type 1 diabetes.
Title:Diabetes & C-Peptide: Scientific and Clinical AspectsFormat:HardcoverDimensions:182 pagesPublished:November 3, 2011Publisher:Humana PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:1617793906

ISBN - 13:9781617793905

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Table of Contents

PrefaceForewordChapter 1: C-peptide and Insulin - A Happy Marriage  Donald. F. SteinerChapter 2: Peptide Interactions of Proinsulin C-peptideCharlotte Nerelius, Emma Lindahl, Michael Landreh and Hans JörnvallChapter 3: The Effect of Combined C-peptide and Zinc on Cellular FunctionDana M. SpenceChapter 4: C-Peptide Signaling in the Kidney and Protection from Diabetic Nephropathy  Nigel J. BrunskillChapter 5:  Role of C-Peptide in the Regulation of Microvascular Blood Flow Thomas Forst, Matthias M. Weber, Thomas Kunt, Andreas Pfützner Chapter 6: Is NO-eNOS a target for C-peptide action and its protective effects on diabetic nephropathy?  Kazuhiro Kimura and Akihiro KamikawaChapter 7: Renoprotective Effects of C-Peptide in Type I DiabetesLina Nordquist, ?sa Kallas, Sara Stridh, Fredrik Palm, John Wahren   Chapter 8: The Mechanisms Underlying the Effects of C-peptide on Type I Diabetic NeuropathyHideki Kamiya, Wei-Xian Zhang, Anders A.F. SimaChapter 9: C-peptide and Type 1 Diabetic EncephalopathyAnders A.F. Sima, Wei-Xian ZhangChapter 10: C-peptide: a New Molecule with Anti-Inflammatory PropertiesJaime Haidet, Vincenza Cifarelli, Xuehui Geng, Massimo Trucco, Patrizia LuppiChapter 11: C-peptide: Connecting Diabetes with Macrovascular Complications Karen E. Porter, Romana S. MughalChapter 12: C-peptide and Diabetic Neuropathy in Patients with Type I DiabetesKarin Ekberg, John WahrenChapter 13: Proatherogenic Effects of C-PeptideDaniel Walcher, Nikolaus MarxChapter 14: Conclusions and Future Outlook  Anders A.F. Sima