Dialysis Amyloid

Hardcover | January 1, 1993

EditorCharles van Ypersele, Tilman B. Drueke

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Dialysis amyloidosis is a syndrome observed in dialysis patients characterized initially by joint pain, followed later by joint destruction. It is at present one of the few compliations in these patients. The factors involved in the genesis of this syndrome are not yet known with certainty and there is as yet no proven efficacious treatment otehr then renal transplantation. As a result, the interest in this topic among nephrologists remains very high. Dialysis amyloid gives general information on the pathophysiology, and the clinical aspects of all types of amyloidosis. It then goes on to discuss recently discovered B2, type of dialysis amyloidosis, from clinical and pathological features to physiological and pathophysiological aspects of thisserious complication which effects patients suffering from chronic renal failure. This book will give nephrologists and rheumatologists a clear understanding of the dialysis amyloidosis syndrome as well as making a valuable contribution to identifying strategies for treatment and prevention.

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Dialysis amyloidosis is a syndrome observed in dialysis patients characterized initially by joint pain, followed later by joint destruction. It is at present one of the few compliations in these patients. The factors involved in the genesis of this syndrome are not yet known with certainty and there is as yet no proven efficacious tr...

Charles van Ypersele is at Catholic University of Louvain, Brussels. Tilman B. Drueke is at Hopital Necker, Paris.

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Format:HardcoverDimensions:290 pages, 9.45 × 6.61 × 0.87 inPublished:January 1, 1993Publisher:Oxford University Press

The following ISBNs are associated with this title:

ISBN - 10:0192624946

ISBN - 13:9780192624949

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Table of Contents

Part I: General aspects of amyloidosios1. Pathpophysiology of amyloidogenesis2. Various clinical types of amyloidosisPart II: Clinical characteristics of V2=microglobulin amyloidosis3. Arthropathy and carpal tunnel syndrome of V2-microglobulin amyloidosis4. Radiology of dialysis amyloidosis5. Ultrasonography of the joints6. Whole-body scintigraphyPart III: Pathology of V2-microglobulin deposits7. Composition of V2-microglobulin deposits8. Description, localization, and progression of B2-microglobulin dialysis-related amyloid depositionPart IV: Physiopathology of V2-microglobulin accumulation and deposition9. Characteristics of V2-microglobulin metabolism10. Involvement of V2- microglobulin modified with AGEs in dialysis-related amyloidosis11. Factors modifying removal and production of V2-microglobulin12. Determinants of fibril precipitation and aggregation in amyloid deposits.Part IV: Review of the clinical evidence on the prophylactic and therapeutic approaches to V2-microglobulin amyloidosis13. Prevention and treatment of V2-microglobulin amyloidosis

Editorial Reviews

`In General this is an excellent book and gives much useful information relating to this distressing condition...A useful feature of this book is the extensive list of references at the end of each chapter...The chapters are well written, the book is well balanced, the illustrationsappropriate and the index comprehensive. It is therefore a text which can be recommended to those seeking a greater understanding of the subject.'Nephrol Dial Transplant, 1998, 13: 1904-8