Discovery And Development Of Antidiabetic Agents From Natural Products: Natural Product Drug…

Paperback | November 1, 2016

byGoutam Brahmachari

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Discovery and Development of Antidiabetic Agents from Natural Products brings together global research on the medicinal chemistry of active agents from natural sources for the prevention and treatment of diabetes and associated disorders. From the identification of promising leads, to the extraction and synthesis of bioactive molecules, this book explores a range of important topics to support chemists in the discovery and development of safer, more economical therapeutics that are desperately needed in response to this emerging global epidemic. Beginning with an overview of bioactive chemical compounds from plants with anti-diabetic properties, the book goes on to outline the identification and extraction of anti-diabetic agents and antioxidants from natural sources. It then explores anti-diabetic plants from specific regions before looking more closely at the background, isolation, and synthesis of key therapeutic compounds and their derivatives, including Mangiferin, Resveratrol, natural saponins, and alpha-glucosidase enzyme inhibitors. The book concludes with a consideration of current and potential future applications. Combining the expertise of specialists from around the world, this volume aims to support and encourage medicinal chemists investigating natural sources as starting points for the development of standardized, safe, and effective antidiabetic therapeutics. Contains chapters written by active researchers and leading global experts who are deeply engaged in the research field of natural product chemistry for drug discovery Provides comprehensive coverage of cutting-edge research advances in the design of medicinal natural products with potential as preventives and therapeutics for diabetes and related metabolic issues Presents a practical review of the identification, isolation, and extraction techniques that help support medicinal chemists in the lab

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From the Publisher

Discovery and Development of Antidiabetic Agents from Natural Products brings together global research on the medicinal chemistry of active agents from natural sources for the prevention and treatment of diabetes and associated disorders. From the identification of promising leads, to the extraction and synthesis of bioactive molecules...

From the Jacket

Diabetes is quickly emerging as a global epidemic. In response, research is underway worldwide to produce new drugs with greater safety, economic viability and efficacy, and natural products are proving to be a rich source of active agents for further development.Discovery And Development of Antidiabetic Agents from Natural Productsdra...

Professor Dr. Goutam Brahmachari was born at Barala in the district of Murshidabad (West Bengal), India, on April 14, 1969. He received his high school degree in scientific studies in 1986 at Barala R. D. Sen High School under the West Bengal Council of Higher secondary Education (WBCHSE). Then he moved to Visva-Bharati (a central univ...

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Format:PaperbackDimensions:332 pages, 8.75 × 6.35 × 0.68 inPublished:November 1, 2016Publisher:Elsevier Science & TechLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0128094508

ISBN - 13:9780128094501

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Table of Contents

1. Bioactive Compounds from Plants with Anti-diabetic properties

2. Identification and extraction of anti-diabetic agents from natural sources

3. Identification and extraction of anti-diabetic antioxidants from natural sources

4. Bioactive Compounds from Anti-diabetic Plants of Africa

5. Bioactive Compounds from Anti-diabetic Plants of the Khandesh Region

6. Computer-aided discovery of glycogen phosphorylase inhibitors exploiting natural products

7. Anti-diabetic Natural Saponins

8. Mangiferin: Natural distribution, isolation and synthesis

9. Resveratrol and its synthetic analogues: A survey

10. Alpha-glucosidase enzyme inhibitors from natural products

11. Glucose Transporter 4 (GLUT4) Translocation Activators from Nature

12. Management of Insulin resistance with natural products and their derivatives: Past, present and future prospects

13. Inflammation and diabetes: An update on the therapeutic potency of natural products