Discovery And Development Of Antidiabetic Agents From Natural Products: Natural Product Drug Discovery by Goutam BrahmachariDiscovery And Development Of Antidiabetic Agents From Natural Products: Natural Product Drug Discovery by Goutam Brahmachari

Discovery And Development Of Antidiabetic Agents From Natural Products: Natural Product Drug…

byGoutam Brahmachari

Paperback | October 25, 2016

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Discovery and Development of Antidiabetic Agents from Natural Productsbrings together global research on the medicinal chemistry of active agents from natural sources for the prevention and treatment of diabetes and associated disorders. From the identification of promising leads, to the extraction and synthesis of bioactive molecules, this book explores a range of important topics to support chemists in the discovery and development of safer, more economical therapeutics that are desperately needed in response to this emerging global epidemic.

Beginning with an overview of bioactive chemical compounds from plants with anti-diabetic properties, the book goes on to outline the identification and extraction of anti-diabetic agents and antioxidants from natural sources. It then explores anti-diabetic plants from specific regions before looking more closely at the background, isolation, and synthesis of key therapeutic compounds and their derivatives, including Mangiferin, Resveratrol, natural saponins, and alpha-glucosidase enzyme inhibitors. The book concludes with a consideration of current and potential future applications.

Combining the expertise of specialists from around the world, this volume aims to support and encourage medicinal chemists investigating natural sources as starting points for the development of standardized, safe, and effective antidiabetic therapeutics.



  • Contains chapters written by active researchers and leading global experts who are deeply engaged in the research field of natural product chemistry for drug discovery
  • Provides comprehensive coverage of cutting-edge research advances in the design of medicinal natural products with potential as preventives and therapeutics for diabetes and related metabolic issues
  • Presents a practical review of the identification, isolation, and extraction techniques that help support medicinal chemists in the lab
Professor Dr. Goutam Brahmachari was born at Barala in the district of Murshidabad (West Bengal), India, on April 14, 1969. He received his high school degree in scientific studies in 1986 at Barala R. D. Sen High School under the West Bengal Council of Higher secondary Education (WBCHSE). Then he moved to Visva-Bharati (a central univ...
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Title:Discovery And Development Of Antidiabetic Agents From Natural Products: Natural Product Drug…Format:PaperbackDimensions:332 pages, 8.75 × 6.35 × 0.68 inPublished:October 25, 2016Publisher:Elsevier ScienceLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0128094508

ISBN - 13:9780128094501

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Table of Contents

Chapter 1. Andrographolide: A Molecule of Antidiabetic Promise

Chapter 2. Computer-Aided Discovery of Glycogen Phosphorylase Inhibitors Exploiting Natural Products

Chapter 3. Identification and Extraction of Antidiabetic Antioxidants from Natural Sources

Chapter 4. Glucose Transporter 4 Translocation Activators From Nature

Chapter 5. Carbohydrate-Based Antidiabetic Agents From Nature

Chapter 6. Recent Developments on the Antidiabetic Sesquiterpene Lactones and Their Semisynthetic Analogues

Chapter 7. Prediction of Prediabetes and Its Prevention by Functional Food Compounds

Chapter 8. Immunomodulators in Prophylaxis and Therapy of Type-1 Diabetes

Chapter 9. ± -Glucosidase Enzyme Inhibitors From Natural Products

Chapter 10. Treasures of Indigenous Indian Herbal Antidiabetics: An Overview