Dna Repair Enzymes: Cell, Molecular, And Chemical Biology by Brandt EichmanDna Repair Enzymes: Cell, Molecular, And Chemical Biology by Brandt Eichman

Dna Repair Enzymes: Cell, Molecular, And Chemical Biology

byBrandt Eichman

Hardcover | June 20, 2017

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DNA Repair Enzymes, Part A, Volume 591is the latest volume in theMethods in Enzymologyseries and the first part of a thematic that focuses on DNA repair enzymes. Topics in this new release include chapters on the Optimization of Native and Formaldehyde iPOND Techniques for Use in Suspension Cells, the Proteomic Analyses of the Eukaryotic Replication Machinery, DNA Fiber Analysis: Mind the Gap!, Comet-FISH for Ultrasensitive Strand-Specific Detection of DNA Damage in Single Cells, Examining DNA Double-Strand Break Repair in a Cell Cycle-Dependent Manner, Base Excision Repair Variants in Cancer, and Fluorescence-Based Reporters for Detection of Mutagenesis in E. coli.



  • Includes contributions from leading authorities working in enzymology
  • Focuses on DNA repair enzymes
  • Informs and updates on all the latest developments in the field of enzymology
Dr. Eichman is a Professor of Biological Sciences and Biochemistry at Vanderbilt University, where his laboratory investigates the structural mechanisms of protein machines involved in maintenance of genome integrity. Professor Eichman was initially trained as a synthetic organic chemist at the University of Mississippi (B.S., Chemistr...
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Title:Dna Repair Enzymes: Cell, Molecular, And Chemical BiologyFormat:HardcoverDimensions:478 pages, 9.41 × 7.24 × 0.98 inPublished:June 20, 2017Publisher:Academic PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0128118466

ISBN - 13:9780128118467

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Table of Contents

  1. Optimization of Native and Formaldehyde iPOND Techniques for Use in Suspension Cells
    Nathaniel E. Wiest and Alan E. Tomkinson
  2. Proteomic Analyses of the Eukaryotic Replication Machinery
    David Cortez
  3. DNA Fiber Analysis: Mind the Gap!
    Annabel Quinet, Denisse Carvajal-Maldonado, Delphine Lemacon and Alessandro Vindigni
  4. Comet-FISH for Ultrasensitive Strand-Specific Detection of DNA Damage in Single Cells
    Manas Mondal and Jia Guo
  5. Examining DNA Double-Strand Break Repair in a Cell Cycle-Dependent Manner
    Janapriya Saha, Shih-Ya Wang and Anthony J. Davis
  6. Base Excision Repair Variants in Cancer
    Carolyn G. Marsden, Julie A. Dragon, Susan S. Wallace and Joann B. Sweasy
  7. Fluorescence-Based Reporters for Detection of Mutagenesis in E. coli
    Melissa Standley, Jennifer Allen, Layla Cervantes, Joshua Lilly and Manel Camps
  8. Sequencing DNA for the Oxidatively Modified Base 8-Oxo-7,8-Dihydroguanine
    Aaron M. Fleming, Yun Ding and Cynthia J. Burrows
  9. Xenopus laevis as Model System to Study DNA Damage Response and Replication Fork Stability
    Vincenzo Sannino, Federica Pezzimenti, Stefania Bertora and Vincenzo Costanzo
  10. Ensemble and Single-Molecule Analysis of NHEJ in Frog Egg Extracts
    Thomas Graham, Johannes C. Walter and Joseph J. Loparo
  11. Analysis of Structure-Selective Endonuclease Activities From Yeast and Human Extracts
    Joao Matos and Stephen C. West
  12. Strategies and Methods of Transcription-Coupled Repair Studies In Vitro and In Vivo
    Vitaly Epshtein, Venu Kamarthapu and Evgeny Nudler
  13. Reconstituted System for the Examination of Repair DNA Synthesis in Homologous Recombination
    Youngho Kwon, James M. Daley and Patrick Sung
  14. Current and Emerging Assays for Studying the Primer Synthesis Activities of DNA Primases
    Thomas A. Guilliam and Aidan J. Doherty
  15. Electrical Probes of DNA-Binding Proteins
    Jacqueline K. Barton, Phillip L. Bartels, Yingxin Deng and Elizabeth O Brien
  16. Preparation of Stable Nitrogen Mustard DNA Interstrand Cross-Link Analogs for Biochemical and Cell Biological Studies
    Alejandra Castaño, Upasana Roy and Orlando D. Schärer