DNA Viruses: A Practical Approach by Alan J. CannDNA Viruses: A Practical Approach by Alan J. Cann

DNA Viruses: A Practical Approach

EditorAlan J. Cann

Paperback | October 21, 1999

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DNA Viruses: A Practical Approach groups together the major experimental methods currently employed to study DNA viruses, from the fundamentals of virus culture to novel techniques such as surface plasmon resonance spectrometry and realtime PCR analysis of drug resistance mutations in clinicalisolates. Chapter 1 provides an overview of the extraction, purification and characterizations of virus DNA, but also covers the fundamentals of DNA virus culture. Chapters 2 and 3 describe approaches to the molecular investigation and mutagenesis of DNA virus genomes. Chapter 4 considers DNAvirus replication and then chapters 5 and 6 describe methods to study transcription control. Chapters 7 to 9 consider aspects of the pathogenesis of DNA virus infections. The final chapter describes the current technology being applied to the development of DNA virus vectors for gene delivery.This volume will therefore be of interest to all those working on DNA viruses whether in academia, industry or clinical research.
Alan J. Cann is at University of Leicester.
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Title:DNA Viruses: A Practical ApproachFormat:PaperbackPublished:October 21, 1999Publisher:Oxford University PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0199637180

ISBN - 13:9780199637188

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Table of Contents

Preface1. Haliburton: Extraction, purification and characterization of virus DNA2. Skinner: Investigation of DNA virus genome structure3. Leppard: Mutagenesis of DNA virus genomes4. Botting and Hay: Interactions between viral and cellular proteins during DNA virus replication5. Thomas and Latchman: Analysis of transcriptional control in DNA virus infections6. Meredith and Whitehouse: Identification and analysis of trans-acting proteins involved in regulation of DNA virus gene expression7. Lalani et al: Interaction of DNA virus proteins with host cytokines8. Hall et al: Analysis of DNA virus proteins involved in neoplastic cell transformation9. Pillay: Chemotherapy of DNA virus infections10. Scarpini et al: Herpes simplex virus and adenovirus vectors