Electrophysiology: Basics, Modern Approaches And Applications by Jürgen RettingerElectrophysiology: Basics, Modern Approaches And Applications by Jürgen Rettinger

Electrophysiology: Basics, Modern Approaches And Applications

byJürgen Rettinger, Silvia Schwarz, Wolfgang Schwarz

Hardcover | June 10, 2016

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This textbook presents a broad overview of topics concerning cellular electrophysiology - covering topics ranging from bioelectric phenomena recognized as far back as ancient Egypt to popular topics on the dangers of electrosmog. Without sacrificing scientific precision, this clear and concise work presents on the one hand the different methods and applications, on the other hand the biophysical fundamentals of ion-channel and carrier proteins. Numerous and carefully selected illustrations and diagrams supplement the text, while questions at the end of each chapter allow readers to test their understanding. Each section also includes references to relevant original literature for further reading. The book offers a valuable resource for students of biology, chemistry and physics with a special interest in biophysics.
Dr. phil.nat. Jürgen RETTINGER Product Manager Multi Channel Systems MCS GmbHAspenhaustrasse 2172770 Reutlingen, GermanyJürgen Rettinger received his doctor degree in physics at Goethe-University in Frankfurt. in 1995. His focus as group leader at Max-Planck-Institute of Biophysics in Frankfurt was research of structure-function relati...
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Title:Electrophysiology: Basics, Modern Approaches And ApplicationsFormat:HardcoverDimensions:162 pagesPublished:June 10, 2016Publisher:Springer-Verlag/Sci-Tech/TradeLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:3319300113

ISBN - 13:9783319300115

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Table of Contents


Chapter 1
1     Introduction
1.1   INTRODUCTORY OVERVIEW
1.2   HISTORY OF ELECTROPHYSIOLOGY

Chapter 2
2     Basics: Theory
2.1   ELECTRICAL CHARACTERISTICS OF BIOLOGICAL MEMBRANES
2.2   ION DISTRIBUTION AT BIOLOGICAL MEMBRANES
2.3   DONNAN DISTRIBUTION AND NERNST EQUATION
2.4   GOLDMAN-HODGKIN-KATZ EQUATION

Chapter 3
3.    Basics: Methods
3.1   RECORDING ELECTRICAL SIGNALS FROM BODY SURFACE
3.2   THE EXAMPLE (ECG)
3.3   RECORDING ELECTRICAL SIGNALS FROM TISSUE
3.4   RECORDING ELECTRICAL SIGNALS FROM SINGLE CELLS
3.5   APPLICATION OF THE VOLTAGE-CLAMP TECHNIQUE
3.6   THE PATCH-CLAMP TECHNIQUE

Chapter 4
4     Automated Electrophysiology
4.1   AUTOMATED TWO-ELECTRODE VOLTAGE CLAMP
4.2   AUTOMATED PATCH CLAMP

Chapter 5
5     Ion-selective Channels
5.1   GENERAL CHARACTERISTICS OF ION CHANNELS
5.2   SPECIFIC ION CHANNELS

Chapter 6
6     Theory of Excitability
6.1   THE HODGKIN-HUXLEY DESCRIPTION OF EXCITATION
6.2   CONTINUOUS AND SALTATORY CONDUCTION OF ACTION POTENTIALS
6.3   GENERATION AND TRANSMISSION OF ACTION POTENTIALS
6.4   SUMMARY OF THE DIFFERENT TYPES OF POTENTIALS
6.5   ACTION POTENTIAL IN NON-NERVE CELLS

Chapter 7
7     Carrier-mediated Transport
7.1   GENERAL CHARACTERISTICS OF CARRIERS
7.2   CARRIERS ARE LIKE CHANNELS WITH ALTERNATING GATES

Chapter 8
8     Examples of Application of Electrophysiology
8.1   STRUCTURE-FUNCTION RELATIONSHIPS OF CARRIER PROTEINS
8.2   STRUCTURE-FUNCTION RELATIONSHIPS OF ION CHANNELS
8.3   VIRAL ION CHANNELS

Appendix
A1.   THE GRAPH THEORY
A2.   INFLUENCE OF EXTERNAL ELECTRICAL AND MAGNETIC FIELDS
A2.1. MAGNETOSTATIC FIELDS
A3.   A LABORATORY COURSE:

Important Physical Units
List of Symbols and Abbreviations
Index