Endocrine Disruption: Biological Bases for Health Effects in Wildlife and Humans

Hardcover | September 9, 2005

EditorDavid O. Norris, James A. Carr

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This book addresses the biological effects of the reasonably large number of classes of compounds that have been recognized as endocrine disrupters. These compounds have been found to persist as pollutants in the environment, and have been blamed for causing developmental disorders and/orfertility problems in fish, amphibians, reptiles, birds, and possibly humans. This book presents the relevant fundamentals of the endocrine systems of animals and humans, the toxicology, developmental toxicology, ecology, and risk assessment methods, and lays out the current state of understandingfor the whole field, organized by the classes of compounds that have been identified as endocrine disrupters.

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This book addresses the biological effects of the reasonably large number of classes of compounds that have been recognized as endocrine disrupters. These compounds have been found to persist as pollutants in the environment, and have been blamed for causing developmental disorders and/orfertility problems in fish, amphibians, reptiles...

David O. Norris is at University of Colorado, Boulder. James A. Carr is at Texas Tech University, Lubbock.
Format:HardcoverDimensions:496 pages, 6.42 × 9.21 × 1.1 inPublished:September 9, 2005Publisher:Oxford University PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0195137493

ISBN - 13:9780195137491

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Table of Contents

Part I. Vertebrate Chemical Regulation1. David O. Norris and James A. Carr: Introduction to Endocrinology2. Miles Orchinik and Catherine Propper: Hormone Action on Receptors3. James A. Carr and David O. Norris: The Hypothalamus-Pituitary Axis4. James A. Carr and David O. Norris: The Thyroid Gland5. James A. Carr and David O. Norris: The Adrenal Glands6. James A. Carr and David O. Norris: The GonadsPart II. Toxicology and Risk Assessment7. Richard L. Dickerson and Ernest E. Smith: Introduction to the Science of Toxicology8. Kenneth R. Dixon and Clyde F. Martin: Probablistic Risk Assessment9. Lynn Frame and Richard L. Dickerson: Fish and Wildlife as Sentinels of Environmental ContaminationPart III. Representative EDCs in Animals10. Mary K. Walker: Polychlorinated Dibenzo-p-Dioxins: Potential Mechanisms and Risk as Endocrine Disruptors11. John P. Giesy, K. Kannan, Alan L. Blankenship, Paul D. Jones, and J.L. Newsted: Toxicology of PDBs and Related Compounds12. Louis J. Guillette, Jr., Stefan A.E. Kools, Mark P. Gunderson, and Dieldrich S. Bermudez: DDT and Its Analogues: New Insights into Their Endocrine-Disrupting Effects on Wildlife13. Alice Hontela and Alexandra Lacroix: Heavy Metals14. Werner Kloas: Effects of Alkyphenolic Compounds on Wildlife15. Alan M. Vajda and David O. Norris: Endocrine-Active Phytochemicals: Environmental Signaling Context and Mechanisms16. Timothy S. Gross and R. Heath Rauschenberger: TriazinesAppendices