Engineering the Human Germline: An Exploration of the Science and Ethics of Altering the Genes We…

Hardcover | January 1, 2000

EditorGregory Stock, John Campbell

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This book explores the many prospects, challenges and ethical questions that surround the engineering of our reproductive cells. It is an accessible, three-part examination, moving from focused, realistic assessments of the promise and problems for this advancing technology to a section ofshort essays on the implications of our technological ability. Also included is a panel discussion in which leading scientists, ethicists, and public policy workers give voice to their thoughts and concerns regarding our impending genetic technologies. Many world leaders in these fields, includingLeroy Hood, French Anderson, Mario Capecchi, Daniel Koshland, Michael Rose, Lee Silver, and James Watson, have contributed to this volume, providing the essential elements of the debate over germline engineering. If you have ever pondered the question: "Would I be willing to genetically alter myown child-to-be, given a safe, reliable technology, offering a tempting possibility?", this book will be an indispensable guide.

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This book explores the many prospects, challenges and ethical questions that surround the engineering of our reproductive cells. It is an accessible, three-part examination, moving from focused, realistic assessments of the promise and problems for this advancing technology to a section ofshort essays on the implications of our techno...

Gregory Stock is at UCLA Center for the Study of Evolution and the Origin of Life. John Campbell is at UCLA School of Medicine.

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Format:HardcoverDimensions:192 pages, 9.09 × 6.3 × 0.98 inPublished:January 1, 2000Publisher:Oxford University PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0195133021

ISBN - 13:9780195133028

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Table of Contents

ContributorsIntroduction: An Evolutionary PerspectiveI. THE REALITIES OF HUMAN GERMLINE ENGINEERINGJohn Campbell and Gregory Stock: A Vision for Practical Human Germline EngineeringLeroy Hood: The Human Genome Project--Launch Pad for Human Genetic EngineeringDaniel Koshland, Jr.: Ethics and SafetyMario R. Capecchi: Human Germline Gene Therapy: How and WhyW. French Anderson: A New Front in the Battle against DiseaseMichael R. Rose: Aging as a Target for Genetic EngineeringLee M. Silver: Reprogenetics: How Reproductive and Genetic Technologies Will Be Combined to Provide New Opportunities for People to Reach Their Reproductive GoalsII. THE ROAD AHEADJohn Campbell et al.: A Panel DiscussionIII. OTHER VOICESGlenn McGee et al.: Beyond the Issue of SafetyAlex Mauron et al.: Long-Term Possibilities and DangersDarryl Macer and Lloyd Cohen: Regulation and JurisdictionAppendix: Select Questions from the Public to Participants in the "Engineering the Human Germline" SymposiumNotesGlossaryIndex

Editorial Reviews

"Over the past years new reproductive and molecular technologies, concurrent with progress in the human genome project, have provided a scientific foundation for speculation about manipulation of the human genome. . .In an apparent attempt to address our mixed feelings about human geneticmanipulation, the present book is published. This three part volume tries to address our state of scientific progress in germ-line genetic modification."--Heredity Journal