Enzymes as Catalysts in Organic Synthesis by Manfred P. SchneiderEnzymes as Catalysts in Organic Synthesis by Manfred P. Schneider

Enzymes as Catalysts in Organic Synthesis

byManfred P. Schneider

Paperback | February 12, 2012

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Proceedings of the NATO Advanced Research Workshop, Reisensburg/Ulm, Donau, Germany, June 16-22, 1985
Title:Enzymes as Catalysts in Organic SynthesisFormat:PaperbackDimensions:422 pages, 23.5 × 15.5 × 0.01 inPublished:February 12, 2012Publisher:Springer-Verlag/Sci-Tech/TradeLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:9401085838

ISBN - 13:9789401085830

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Table of Contents

Lectures.- Baker's yeast mediated preparation of carbohydrate-like chiral synthons.- Alcohol dehydrogenase catalysed oxidoreduction reactions in organic chemistry.- On the use of viologen dyes for stereospecific bioreduction.- Approaches to chiral building blocks for natural product synthesis.- Use of microorganisms for the resolution of synthetically useful bicyclo[ 3.2.0] hept-2-en-6-ones.- The scope of biocatalysts in organic chemical processing.- Enantioselective synthesis of biologically active cyclopentanoids via enzyme catalysed asymmetric reactions.- Creation of novel chiral synthons with pig liver esterase: application to natural product synthesis and the substrate recognition.- Application of microbial transformations in the total synthesis of natural products.- Approaches to chiral building blocks for natural products synthesis.- Synthesis of enantiomerically pure unnatural compounds via non-biomimetic homoaldol reactions.- Aldolases as catalysts in organic synthesis.- Immobilised redox enzymes and their use as catalysts for fine chemical synthesis.- Applications of microbes and microbial enzymes in environmental control and organic synthesis.- Synthesis of chirally labelled substrates using enzymes.- Synthesis of L-amino acids by isolated enzymes and microorganisms.- Development of an enzyme reactor for food chemistry.- Preparation and properties of semisynthetic flavoenzymes.- The study and redesign of enzymes by protein engineering.- Evolutionary guidance and the engineering of enzymes.- Posters.- Baker's yeast mediated synthesis of protected ?-hydroxyaldehydes.- Enantioselective PLE-catalyzed hydrolysis of meso-dimethyl tetrahydrophthalate on a 100 mole scale - protection of the enzyme by addition of bovine serum albumin.- Enantio- and diastereoselectivity of microsomal epoxide hydrolase: potential applications to the preparation of non-racemic epoxides and diols.- Efficient enzymic production of enantiomerically pure amino acids.- Biohydroxylation of non activated carbon atoms. A model for the hydroxylation site of the fungus beauveria sulfurescens.- "Sterols Bioconversions in systems with an organic phase".- Second-generation biocatalysis.- Round-table discussions.- I. Nicotinamide recycling.- II. Enzymatic hydrolysis of nitriles, amides, urethanes and carbonates.- III. Enzymes in organic solvents. Enzymatic esterification.- IV. General discussion "Where do we go?". Conclusions and suggestions.- - Chiral building blocks.- - Role of enzymes in protection and deprotection.- - Regioselective reactions using enzymes.- - New areas for enzyme applications.- - Artificial coenzymes, genetic - and proteinengineering.- - Requests from synthetic organic chemists.- - Final remarks.- List of contributors.