Epidemiological Methods In Life Course Research by Andrew PicklesEpidemiological Methods In Life Course Research by Andrew Pickles

Epidemiological Methods In Life Course Research

EditorAndrew Pickles, Barbara Maughan, Michael Wadsworth

Paperback | September 1, 2007

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Life course epidemiology is concerned with the origins of risk, resilience, and the processes of ageing, and how this information can be of value in a public health context - particularly for preventive health care. Its challenge is to discover, develop and analyse sources of data that covermany years of life, especially the early developmental period when, it is thought, some fundamental aspects of lifetime health begin. It also analyses genetic propensity and environmental exposures. The rapid development of life course epidemiology, in parallel with new work on developmental biology and the biology of ageing, has bought innovative and ingenious methods of data collection. These require new methodological techniques for the design of observational and quasi-experimental studiesof life course pathways to adult health. This book describes these developments, together with arguments for improving the measurement of the social environment and its role in developing individual vulnerability or adaptation. The development of bio-bank large-scale population studies for theinvestigation of genetic effects is discussed, alongside the challenges this creates for the epidemiologist. The changing design of studies, increasing flow of longitudinal data, management of data, analytic challenges, timing, and both traditional and more recent methods of managing these featuresin the study of causality, are discussed. Life course epidemiology has an essential role in developing methods to evaluate precisely the impact of interacting developmental, environmental, and genetic effects, knowledge of which is fundamental for the design of effective prevention strategies in public health, as well as for theadvancement of understanding in the broader spheres of health and medicine.
Andrew Pickles is a methodologist and statistician with a special interest in developmental psychopathology. His work spans genetics to long-term cohort and follow-up studies. Currently at the University of Manchester, he was previously senior statistician at the MRC Child Psychiatry Unit at the Institute of Psychiatry, London. Barba...
Title:Epidemiological Methods In Life Course ResearchFormat:PaperbackDimensions:272 pages, 9.69 × 6.73 × 0.55 inPublished:September 1, 2007Publisher:Oxford University PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0198528485

ISBN - 13:9780198528487

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Table of Contents

1. Michael Wadsworth, Barbara Maughan and Andrew Pickles: Introduction: development and progression of life course ideas in epidemiology2. Jane Costello and Adrian Angold: Measurement and design for life course studies of individual differences and development3. Barbara Maughan and Michael Wadsworth: Measurement and design for life course studies of the social environment and its impact on health4. Camilla Stoltenberg and Andrew Pickles: Designs for large life course studies of genetic effects5. Clyde Hertzman: Human development, life course, intervention and health6. Tim Cole: The life course plot in life course analysis7. Paul Clarke and Rebecca Hardy: Methods for handling missing data8. Andrew Pickles and Bianca De Stavola: An overview of models and methods for life course analysis9. Andrew Pickles and Bianca De Stavola: An overview of methods for studying events and their timing