Epigenetic Principles of Evolution by Nelson R. CabejEpigenetic Principles of Evolution by Nelson R. Cabej

Epigenetic Principles of Evolution

byNelson R. CabejEditorNelson R. Cabej

Hardcover | November 21, 2011

Pricing and Purchase Info


Earn 1,065 plum® points

Prices and offers may vary in store


In stock online

Ships free on orders over $25

Not available in stores


This is the first and only book, so far, to deal with the causal basis of evolution from an epigenetic view. By revealing the epigenetic "user" of the "genetic toolkit", this book demonstrates the primacy of epigenetic mechanisms and epigenetic information in generating evolutionary novelties.

The author convincingly supports his theory with a host of examples from the most varied fields of biology, by emphasizing changes in developmental pathways as the basic source of evolutionary change in metazoans.

  • Original and thought provoking--a radically new theory that overcomes the present difficulties of the theory of evolution
  • Is the first and only theory that uses epigenetic mechanisms and principles for explaining evolution of metazoans
  • Takes an integrative approach and shows a wide range of learning
Dr. Nelson R. Cabej is the author of Epigenetic Principles Of Evolution (Elsevier, 2011) and Building The Most Complex Structure On Earth (Elsevier, 2013), in which he examines the role of epigenetic mechanisms in organismal evolution. He has published more than 40 scientific articles and 10 books in English and his native language of ...
Title:Epigenetic Principles of EvolutionFormat:HardcoverDimensions:846 pages, 9 × 6 × 0.98 inPublished:November 21, 2011Publisher:Elsevier ScienceLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0124158315

ISBN - 13:9780124158313

Look for similar items by category:


Table of Contents


Part 1: Epigenetic Basis of Metazoan Heredity

  1. Control Systems and Determination of Phenotypic Traits in Metazoans
  2. Neural Manipulation of Gene Expression
  3. Epigenetic Control of Reproduction
  4. Epigenetic Control of Early Development
  5. Neural Control of Postphylotypic Development
  6. The Epigenetic System of Heredity An Outline
  7. Part 2: Neural-Developmental Premises of Evolutionary Adaptation

  8. Evolution and Stress Responses to Changes in Environment
  9. Behavioral Adaptation to Changed Conditions of Living
  10. Ontology: The Workshop of Evolutionary Change
  11. Intragenerational Developmental Plasticity
  12. Part 3: Epigenetics of Circumevolutionary Phenomena and the Mechansim of the Evolutionary Change

  13. Transgenerational Developmental Plasticity An Epitome of Evolutionary Change
  14. Evolution of Metazoans and Their Control System
  15. Part 4: Epigenetics of Metazoan Evolution

  16. Origins of Evolutionary Novelty
  17. Evolution by Loss
  18. Evolution by Reverting to Ancestral Characters
  19. Neural Crest-Determined Evolutionary Novelties
  20. Evolutionary Convergences: The Trend Toward Sameness in Metazoan Evolution
  21. Species and Allopatric Speciaition
  22. Epigentics of Sympatric Speciation Speciation as a Mechanism of Evolution

Editorial Reviews

"Cabej (biology, U. of Tirana, Albania) explains the epigenetic principles of evolution (as opposed to the theory of evolution as determined by changes in genes) and reconstructs the developmental mechanisms of evolutionary changes in metazoans, based on empirical evidence. He focuses on the mechanisms of the generation of the evolutionary innovations from the influence of environment on heredity rather than the role of natural selection. He discusses control systems and determination of phenotypic traits in metazoans, neural manipulation of gene expression, epigenetic control of reproduction and early development, neural control of postphylotypic development, and the epigenetic system of inheritance. He follows with description of neural-developmental premises of evolutionary adaptation, including evolution and stress responses and behavioral adaptation to changes in environment, ontogeny, and intragenerational developmental plasticity; epigenetics of circumevolutionary phenomena and the mechanism of evolutionary change, including transgenerational developmental plasticity and the evolution of metazoans and their control system; and the origins of evolutionary novelty, evolution by loss or by reverting to ancestral characters, neural crest-determined evolutionary novelties, evolutionary convergences, species and allopatric speciation, and sympatric speciation. He presents the available evidence for his theory, rather than illustrating an established theory, and includes a comparative presentation of the neo-Darwinian view to his epigenetic explanation. There is no index."--Reference and Research Book News, October 2012