Epigenetic Regulation of Lymphocyte Development by Cornelis MurreEpigenetic Regulation of Lymphocyte Development by Cornelis Murre

Epigenetic Regulation of Lymphocyte Development

byCornelis Murre

Paperback | February 22, 2014

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The studies described in this volume serve as a starting point to familiarize one self with the multifarious differences in epigenetic designs that orchestrate the progression of developing blood cells. They also may serve as a general paradigm for the mechanisms that underpin the control of eukaryotic gene expression.

Title:Epigenetic Regulation of Lymphocyte DevelopmentFormat:PaperbackDimensions:194 pages, 23.5 × 15.5 × 1.73 inPublished:February 22, 2014Publisher:Springer-Verlag/Sci-Tech/TradeLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:3642447678

ISBN - 13:9783642447679

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Table of Contents

Preface.- Roles of lineage-determining transcription factors in establishing open chromatin - lessons from high-throughput studies.- B Lymphocyte Lineage Specification, Commitment and Epigenetic Control of Transcription by Early B Cell Factor 1.- Epigenetic features that regulate IgH locus recombination and expression.- Local and global epigenetic regulation of V(D)J recombination.- Genetic and Epigenetic Regulation of TCRbeta Gene Assembly.- T-cell identity and epigenetic memory.- Encoding stability versus flexibility: Lessons learned from examining epigenetics in T helper cell differentiation.- The epigenetic landscape of lineage choice: lessons from the heritability ofCd4andCd8expression.- Subject Index