Essential Pharmacokinetics: A Primer For Pharmaceutical Scientists

Paperback | April 1, 2015

byThorsteinn LoftssonEditorThorsteinn Loftsson

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Essential Pharmacokinetics: A Primer for Pharmaceutical Scientists is an introduction to the concepts of pharmacokinetics intended for graduate students and new researchers working in the pharmaceutical sciences. This book describes the mathematics used in the mammillary model as well as the application of pharmacokinetics to pharmaceutical product development, and is useful as both a self-study and classroom resource. Content coverage includes detailed discussions of common models and important pharmacokinetic concepts such as biological half-life, clearance, excretion, multiple dosage regimens and more. Numerous equations, practical examples and figures are incorporated to clearly illustrate the theoretical background of pharmacokinetic behavior of drugs and excipients. Shows how to apply basic pharmacokinetic methods to evaluate drugs, excipients and drug products Uses guided practice questions, mathematical concepts and real-world examples for self-assessment and retention purposes Illustrates how to write and evaluate drug registration files

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From the Publisher

Essential Pharmacokinetics: A Primer for Pharmaceutical Scientists is an introduction to the concepts of pharmacokinetics intended for graduate students and new researchers working in the pharmaceutical sciences. This book describes the mathematics used in the mammillary model as well as the application of pharmacokinetics to pharmaceu...

Dr. Thorsteinn Loftsson is a Professor of Physical Pharmacy at the University of Iceland in Reykjavik. He received his MS Pharm degree from University of Copenhagen and his MS and PhD degrees from the Department of Pharmaceutical Chemistry at the University of Kansas. Dr. Loftsson has authored or co-authors over 200 papers in peer-revi...

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Format:PaperbackDimensions:178 pages, 8.75 × 6.35 × 0.68 inPublished:April 1, 2015Publisher:Academic PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0128014113

ISBN - 13:9780128014110

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Table of Contents

Preface

Chapter 1 - Introduction Chapter 2 Basic Concepts of Pharmacokinetics Chapter 3 - Physicochemical Properties and Pharmacokinetics Chapter 4 - Drug Pharmacokinetics After Alternative Routes of Administration Chapter 5 - Pharmacologic Response and Drug Dosage Adjustments Chapter 6 - The Effect of Food and Exipients on Drug Pharmacokinetics Chapter 7 - Practice Problems

Appendix I: Answers to Problems in Chapter 7 Appexndix II: Symbols and Abbreviations

Editorial Reviews

"...a valuable introductory reference book...By the end of the book, the reader should have a good grasp of the components of pharmacokinetics."--The Pharmaceutical Journal, Essential Pharmacokinetics