Expression Profiling in Neuroscience by Yannis KaramanosExpression Profiling in Neuroscience by Yannis Karamanos

Expression Profiling in Neuroscience

EditorYannis Karamanos

Hardcover | January 5, 2012

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Transcriptomics and proteomics, studying the profile of the expression of nucleic acids and proteins respectively, are increasingly applied to gain a mechanistic insight into a wide spectrum of investigation, and the use of expression profiling studies for the central nervous system and brain function aids in the understanding of neurodegenerative disorders and tumor development mechanisms.  In Expression Profiling in Neuroscience, expert researchers provide a survey of the most commonly used approaches in the field and scan the different ways of studying the central nervous system/brain environment through expression profiling.  The first part addresses the gene expression profiling of the brain at a large scale or to a specific cell type such as blood-brain barrier endothelium. Then, the second part describes the protein expression studies and the different technologies applied.  Written for the popular Neuromethods series, chapters include corresponding background information, tested laboratory protocols, and step-by-step methods for reproducible laboratory experiments. Detailed and authoritative, Expression Profiling in Neuroscience presents the state-of-the-art techniques necessary to expand research further into this vital area of study.
Title:Expression Profiling in NeuroscienceFormat:HardcoverDimensions:297 pagesPublished:January 5, 2012Publisher:Humana PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:1617794473

ISBN - 13:9781617794476

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Table of Contents

1. DNA Microarrays for Gene Expression Analysis in Brain Tissue and Cell Lines            Gustavo A. Barisone and Elva Díaz 2. Gene Expression Profiling Using the Terminal Continuation (TC) RNA Amplification Method for Small Input Samples in Neuroscience            Stephen D. Ginsberg, Melissa J. Alldred, and Shaoli Che 3. Expression Profiling In Brain Disorders            Peter J. Gebicke-Haerter 4. Endothelial Cell Heterogeneity of Blood-Brain Barrier Gene Expression: Analysis by LCM/qRT-PCR            Tyler Demarest, Nivetha Murugesan, Jennifer Macdonald, and Joel S. Pachter 5. Gene Expression Profiling Using 3' Digital Tag Approach            Yan W. Asmann, E. Aubrey Thompson, and Jean-Pierre A. Kocher 6. Sharing Expression Profiling Data with Gemma            Anton Zoubarev and Paul Pavlidis 7. Two-Dimensional Protein Analysis of Neural Stem Cells            Martin H. Maurer 8. iTRAQ Proteomics Profiling of Regulatory Proteins During Oligodendrocyte Differentiation            Mohit Raja Jain, Tong Liu, Teresa L. Wood, and Hong Li 9. Protein Profiling of the Brain: Proteomics of Isolated Tissues and Cells            Nicole Haverland and Pawel Ciborowski 10. The Proteome of Brain Capillary Endothelial Cells: Towards a Molecular Characterization of an In Vitro Blood-Brain Barrier Model            Sophie Duban-Deweer, Christophe Flahaut, and Yannis Karamanos 11. MALDI Imaging Technology Application in Neurosciences: From History to Perspectives            Michel Salzet, Céline Mériaux, Julien Franck, Maxence Wistorski, and Isabelle Fournier 12. Profiling of HIV Proteins in Cerebrospinal Fluid            Melinda Wojtkiewicz and Pawel Ciborowski 13. Proteomic Profiling of Cerebrospinal Fluid            Gwenael Pottiez and Pawel Ciborowski 14. New Nanotechnology Applications in Single Cell Analysis: Why and How?            Gradimir N. Misevic, Gerard BenAssayag, Bernard Rasser, Philippe Sales, Jovana Simic-Krstic, Nikola Misevic, and Octavian Popescu