Fatty Acids: Physiological and Behavioral Functions by David I. MostofskyFatty Acids: Physiological and Behavioral Functions by David I. Mostofsky

Fatty Acids: Physiological and Behavioral Functions

EditorDavid I. Mostofsky

Paperback | November 9, 2010

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Leading academic and biomedical researchers comprehensively review the status of essential fatty acids (EFA) in nutrition, medicine, psychology, and pharmacology. Topics range from a discussion of EFA basic mechanisms to their effects on individual psychiatry and behavior, and include extensive coverage of pathology, DHA in CNS development, and phospholipid and fatty acid composition and metabolism. Comprehensive and forward-looking, Fatty Acids: Physiological and Behavioral Functions reviews and critically evaluates our current knowledge of EFA, setting the stage for oncoming wave of discovery about the biochemical and molecular functions of essential fatty acids, as well as their critical role in human physiology, immunology, and behavior.
Title:Fatty Acids: Physiological and Behavioral FunctionsFormat:PaperbackDimensions:461 pages, 10 × 7.01 × 0 inPublished:November 9, 2010Publisher:Humana PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:161737265X

ISBN - 13:9781617372650

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Table of Contents

Part I. Basic MechanismsEvolutionary Aspects of Diet: Essential Fatty AcidsArtemis P. SimopoulosModulation of Receptor Signaling by Phospholipid Acyl Chain CompositionDrake C. Mitchell and Burton J. LitmanRole of Docosahexaenoic Acid in Determining Membrane Structure and Function: Lessons Learned from Normal and Neoplastic LeukocytesLaura J. Jenski and William StillwellEffects of Essential Fatty Acids on Voltage-Regulated Ionic Channels and Seizure Thresholds in AnimalsRobert A. Voskuyl and Martin VreugdenhilRole of Dietary Fats and Exercise in Immune Functions and AgingJaya T. Venkatraman and David PendergastPart II. Phospholipid and Fatty Acid Composition and MetabolismOn the Relative Efficacy of _-Linolenic Acid and Preformed Docosahexaenoic Acid as Substrates for Tissue Docosahexaenoate During Perinatal DevelopmentMeng-Chuan Huang and J. Thomas BrennaRecent Advances in the Supply of Docosahexaenoic Acid to the Nervous SystemRobert J. Pawlosky and Norman Salem JrQuantifying and Imaging Brain Phospholipid Metabolism In Vivo Using Radiolabeled Long Chain Fatty AcidsStanley I. RapoportCarbon Recycling: An Important Pathway in _-Linolenate Metabolism in Fetuses and NeonatesStephen C. CunnanePart III. DHA and CNS DevelopmentImpact of Dietary Essential Fatty Acids on Neuronal Structure and FunctionM. Thomas Clandinin, R.A.R. Bowen, and Miyoung SuhDietary N-3 Fatty Acid Deficiency and its Reversibility: Effects upon Brain Phospholipids and the Turnover of Docosahexaenoic Acid in the Brain and BloodWilliam E. Connor, Gregory J. Anderson, and Don S. LinThe Role of Omega-3 Polyunsaturated Fatty Acids in Retinal FunctionAlgis J. Vingrys, James A. Armitage, Harrison S. Weisinger, B.V. Bui, Andrew J. Sinclair, and Richard S. WeisingerBrightness-Discrimination Learning Behavior and Retinal Function Affected by Long-Term _-Linolenic Acid Deficiency in Rat, Harumi OkuyamaYoichi Fujii, and Atsushi IkemotoPart IV. PathologyDisturbances of Essential Fatty Acid Metabolism in Neural Complications of DiabetesJoseph Eichberg and Cristinel MîineaDocosahexaenoic Acid Therapy for Disorders of Peroxisome BiogenesisHugo W. Moser and Gerald V. RaymondEffects of Fatty Acids and Ketones on Neuronal Excitability: Implications for Epilepsy and its Treatment Carl E. StafstromFatty Acid Ethyl Esters: Toxic Nonoxidative Metabolites of EthanolZbigniew M. Szczepiorkowski and Michael LaposataPart V. Psychiatry and BehaviorOmega-3 Fatty Acids and Psychiatric Disorders: Current Status of the FieldJoseph R. Hibbeln and Norman Salem JrDisorders of Phospholipid Metabolism in Schizophrenia, Affective Disorders, and Neurodegenerative DisordersDavid F. HorrobinEicosapentaenoic Acid: A Potential New Treatment for Schizophrenia?Malcolm Peet and Shaun RylesThe Importance of DHA in Optimal Cognitive Function in RodentsClaus C. Becker and David J. KyleThe Role of Omega-3 Polyunsaturated Fatty Acids in Body Fluid and Energy HomeostasisRichard S. Weisinger, James A. Armitage, Peta Burns, Andrew J. Sinclair, Algis J. Vingrys, and Harrison S. WeisingerPUFA: Mediators for the Nervous, Endocrine, and Immune SystemsShlomo Yehuda, Sharon Rabinovitz, and David I. Mostofsky

Editorial Reviews

From the reviews:"This book represents the state of the art on EFA physiology and function. Some chapters are finely written. Particularly interesting are those dealing with the evolutionary aspects of diet, the importance of DHA in central nervous system development, and the role of EFA in cognitive function and psychiatric disorders....The editors...must be congratulated for expediting the publication of this timely and important textbook. It looks to the future, and sets the stage for what is becoming an exciting field of research. Lipid biochemists, nutritionists, developmental biologists and neuroscientists would benefit from this book. Academic libraries must have copies of it..." - Canadian Journal Gastroenterol"Of interest to nutritionists, psychiatrists and basic investigators in these fields, such as psycho-pharmacologists, but also neonatologists may find some interesting data on metabolic influences on brain development." - Journal of Pediatric Endocrinology & Metabolism"The book is successfully edited by three experts...the 23 chapters are written by additional specialists, resulting in an impressive gathering of expertise. The book is clear and easy to grasp through a brief study...the book is a goldmine for anybody interested in current nutrition and medical aspects of fatty acids." - Scandinavian Journal of Nutrition"The book will undoubtedly stimulate further research in these fields. It can be recommended to all scientists interested in the fundamental aspects of nutrition." - Acta Cardiologica"The book gives detailed reviews of biochemical and molecular functions of essential fatty acids(EFA) under consideration of their role in different associated fields like human physiology, immunology, health and disease prevention as well as behavioral functions, just to name a few of them." - Nahrung/Food"...Fatty Acids is timely and can help lipid researchers to catch up with the most recent knowledge in the field. I strongly recommend this book for PUFA researchers. It is also a must for postgraduate students in this field." European Journal of Lipid Science and Technology"...this is an exciting monograph that hopefully will bring the importance of the essential fatty acids to the attention of a wide body of basic and clinical neuroscientists as well as the increasing band of researchers who are interested in 'nutripharmaceuticals'. Monographs such as this help to give credibility to the old adage 'we are what we eat' but, as many of the authors of this volume emphasize, much remains to be discovered regarding the mechanism whereby the essential fatty acids produce their diverse biological effects." -Human Psychopharmacology"...provides a great deal of information about fatty acid activities across a number of disciplines." - Today's Life Science"Collectively, more than 2000 citations provide adequate documentation of the information in the 420 pages and 23 chapters by authors with recognized expertise in the areas of their respective contributions. These contributors discuss the role of EFAs in metabolism, immunity, aging, perinatal development, and psychiatric, neurologic, and cognitive disorders in considerable detail. . this book is worth owning and reading by everyone interested in increasing familiarity with the subject." (Barry S. Kendler, American Journal of Clinical Nutrition, Vol. 22, July, 2006)