Fibrinolytic And Antithrombotic Therapy: Theory, Practice, and Management by Richard C. BeckerFibrinolytic And Antithrombotic Therapy: Theory, Practice, and Management by Richard C. Becker

Fibrinolytic And Antithrombotic Therapy: Theory, Practice, and Management

byRichard C. Becker, Frederick A. Spencer

Paperback | April 11, 2006

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Thrombotic disorders of the circulatory system represent the leading cause of morbidity, motality, and health care expenditure in the United States. Fibrinolytic and Antithrombotic Therapy provides a practical, evidence-based approach to the management of thrombotic disorders for allclinicians involved in the care of patients with these disorders. It provides not only vital conceptual information on fibrinolytic and antithrombotic therapy, but also the means to apply it to everyday decision making and patient care. Focusing on managment guidelines and critical pathways, thetext stresses practicality and usability. It will be a valuable resource for the wide range of clinicians involved in the care of patients with these disorders, including cardiologists, emergency physicians, primary care physicians, hematologists, neurologists, intensivists, pharmacists, and nursepractitioners. The origins of mammalian blood coagulation can be traced back over 400 million years. Despite its long history, it is only within the past century that this complex and pivotal teleologic system has begun to be understood. Most recently, the intricacies of hemostasis and pahtologic thrombosis havecome to light, leading the way toward new, more effective, and safer treatment modalities. The Second Edition of Fibrinolytic and Antithrombotic Therapy, even more concise and clinically relevant than the First, provides vital, evidence-based information on management of patients with arterial and venous thrombotic disorders. Since the First Edition, the text has been expanded to coverthe evolving topics of atherothrombosis, thrombocardiology, hematologic/thrombophilic conditions, and vascular medicine. It includes up-to-date guidelines for antithrombotic and fibrinolytic therapy, and offers concise summaries of current "standards of care." Chapters are dedicated to discussionsof patient-specific therapeutics and to the importance of genomics, proteomics, and metabolomics in defining genotype-phenotype relationships, while throughout the book coagulation, inflammation, and vascular medicine are newly examined as elements in an intricatley-linked triad of biochemical andcellular based phenomenology.
Richard C. Becker is at Duke University Medical Center. Frederick A. Spencer is at McMaster University Faculty of Health Sciences.
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Title:Fibrinolytic And Antithrombotic Therapy: Theory, Practice, and ManagementFormat:PaperbackDimensions:424 pages, 5.51 × 8.19 × 0.71 inPublished:April 11, 2006Publisher:Oxford University PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0195155645

ISBN - 13:9780195155648

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Table of Contents

Part I: Fundamental Scientific Principles1. Historical Perspectives of Hemostasis, Coagulation, and Fibrinolysis2. Vascular Biology, Thromboresistance and Inflammation3. Atherosclerosis and Arterial Thrombosis4. Venous Thromboembolism5. Cardiac Chamber, Aortic and Valvular ThromboembolismPart II: Fibrinolytics and Platelet Antagonists6. Fibrinolytic Agents7. Asprin8. Clopidogrel9. GPIIb/IIIa Receptor Antagonists10. Aggrenox and Cilostazol11. Novel Platelet Antagonists12. Combination Pharmacotherapy13. Facilitated Percutaneous Coronary InterventionsPart III: Anticoagulants14. Thrombin-Directed Therapy15. Factor Xa Inhibitors16. Direct Thrombin Inhibitors17. Novel AnticoagulantsPart IV: Management of Arterial Thrombotic Disorders18. Acute Coronary Syndromes19. Peripheral Vascular Disease and Stroke20. Valvular Heart Disease and Atrial Fibrillation21. Plaque Stabilizing TherapiesPart V: Management of Venous Thrombotic Disorders22. Venous Thromboembolism Prophylaxis23. Venous Thromboembolism TreatmentPart VI: Genomics, Proteomics and Suspected Thrombophilias24. Fundamentals and Patient EvaluationPart VII: Monitoring Antithrombotic Therapy25. Platelet Antagonists26. Antocoagulants27. Anticoagulation Clinics and Self-TestingPart VIII: Complication of Treatment and Their Management28. Platelet Antagonists29. Anticoagulants30. Fibrinolytic AgentsAppendixA. PharmacopeiaPlatelet AntagonistsFibrinolytic AgentsB. Drug Dosing with Renal Insufficiency

Editorial Reviews

"This is an excellent overview for anyone who wishes to develop a broader knowledge of the agents and disorders. It is very well conceived and executed both in content and organization."--Doody's