Fidelity and quality control in gene expression

Hardcover | January 27, 2012

byAssen MarintchevEditorAssen Marintchev

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The goal of this volume is to provide a comprehensive mechanistic and quantitative view of the processes that mediate or influence the quality control in translation. In addition to discussing processes with direct contribution to translation fidelity, such as aminoacylation of tRNAs and translation elongation itself, special attention is given to other processes with impact on quality control: detection and elimination of defective mRNAs, recycling and translation re-initiation, mRNA editing, and translational recoding through programmed frame-shifting. Provides a comprehensive mechanistic and quantitative view of the processes that mediate or influence the quality control in translation Special attention is given to other processes with impact on quality control: detection and elimination of defective mRNAs, recycling and translation re-initiation, mRNA editing, and translational recoding through programmed frame-shifting

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The goal of this volume is to provide a comprehensive mechanistic and quantitative view of the processes that mediate or influence the quality control in translation. In addition to discussing processes with direct contribution to translation fidelity, such as aminoacylation of tRNAs and translation elongation itself, special attention...

Format:HardcoverDimensions:272 pages, 9 × 6 × 0.98 inPublished:January 27, 2012Publisher:Academic PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0123864976

ISBN - 13:9780123864970

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Table of Contents

  1. Quality Control in Aminoacyl-tRNA Synthesis: Its Role in Translational Fidelity Srujana S. Yadavalli and Michael Ibba
  2. Termination and Post-Termination Events in Eukaryotic Translation
  3. Richard J. Jackson, Christopher U.T. Hellen and Tatyana V. Pestova

  4. Quality Control of mRNA Decoding on the Bacterial Ribosome
  5. Marina V. Rodnina

  6. Control of Gene Expression by Translational Recoding
  7. Jonathan D. Dinman

  8. The tmRNA Ribosome Rescue System
  9. Brian D. Janssen and Christopher S. Hayes

  10. Posttranscriptional Recoding by RNA Editing Stefan Maas