Field Trials of Health Interventions: A Toolbox

Paperback | June 25, 2015

EditorPeter G. Smith, Richard H. Morrow, David A. Ross

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This is an open access title. It is available to read and download as a free PDF version at Oxford Medicine Online. It has been made available under a Creative Commons Attribution-Non Commercial [No Derivatives] 4.0 International licence.Before new interventions are released into disease control programmes, it is essential that they are carefully evaluated in "field trials". These may be complex and expensive undertakings, requiring the follow-up of hundreds, or thousands, of individuals, often for long periods. Descriptions of thedetailed procedures and methods used in the trials that have been conducted have rarely been published. A consequence of this, individuals planning such trials have few guidelines available and little access to knowledge accumulated previously, other than their own. In this manual, practical issues in trial design and conduct are discussed fully and in sufficient detail, that Field Trials of Health Interventions may be used as a "toolbox" by field investigators. It has been compiled by an international group of over 30 authors with direct experience in thedesign, conduct, and analysis of field trials in low and middle income countries and is based on their accumulated knowledge and experience.Available as an open access book via Oxford Medicine Online, this new edition is a comprehensive revision, incorporating the new developments that have taken place in recent years with respect to trials, including seven new chapters on subjects ranging from trial governance, and preliminary studiesto pilot testing.

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This is an open access title. It is available to read and download as a free PDF version at Oxford Medicine Online. It has been made available under a Creative Commons Attribution-Non Commercial [No Derivatives] 4.0 International licence.Before new interventions are released into disease control programmes, it is essential that they ar...

Peter G. Smith is Professor of Tropical Epidemiology with the Medical Research Council Tropical Epidemiology Group at London School of Hygiene and Tropical Medicine London, UK. Richard H. Morrow is Professor of International Health, Division of Health Systems, Department of International Health at The Johns Hopkins Bloomberg School of ...

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Format:PaperbackDimensions:480 pages, 9.21 × 6.14 × 0.01 inPublished:June 25, 2015Publisher:Oxford University PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0198732864

ISBN - 13:9780198732860

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Table of Contents

1. Introduction2. Types of intervention and their development3. Reviewing the literature4. Study design5. Study size6. Ethical considerations7. Trial governance8. Preparing grant applications9. Community engagement10. Censuses and mapping11. Randomisation, blinding and coding12. Outcome measures and case definition13. Preliminary studies and pilot testing14. Questionnaires15. Social and behavioural research16. Field organization and ensuring data of high quality17. Field laboratory methods18. Budgeting and accounting19. Intervention costing and economic analysis20. Data management21. Methods of analysis22. Phase IV studies23. Reporting and using trial results

Editorial Reviews

"The editors have effectively distilled a wealth of knowledge into a compact volume in a style that reflects the intention that it should be used as a reference manual or 'toolbox' by field investigators ... a well-written, concise and practical manual." --Paul Pharoah, International Journal of Epidemiology, 22/3, June 1993 03/03/1994