Free Radicals In Biology And Medicine

Paperback | March 15, 2007

byBarry Halliwell, John Gutteridge

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Free Radicals in Biology and Medicine has become a classic text in the field of free radical and antioxidant research since its first publication in 1985. This latest edition has been comprehensively rewritten and updated (over 80% of the text is new), whilst maintaining the clarity of its predecessor. There is expanded coverage of isoprostanes and related compounds, mechanisms of oxidative damage to DNA and proteins (and the repair of such damage),the free radical theory of ageing and the roles played by reactive species in signal transduction, cell death, human reproduction, and other important biological events. Greater emphasis has also been placed on the methods available to measure reactive species and oxidative damage (and theirpotential pitfalls), as well as the importance of antioxidants in the human diet. This book is recommended as a comprehensive introduction to the field for students, clinicians and researchers, and an invaluable companion to all those interested in the role of free radicals in the life and biomedical sciences.

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From the Publisher

Free Radicals in Biology and Medicine has become a classic text in the field of free radical and antioxidant research since its first publication in 1985. This latest edition has been comprehensively rewritten and updated (over 80% of the text is new), whilst maintaining the clarity of its predecessor. There is expanded coverage of iso...

Professor Barry Halliwell is Executive Director of the Graduate School for Integrative Sciences and Engineering and the Head of the Department of Biochemistry of the National University of Singapore John M. C. Gutteridge has retired from mainstream research but remains an active visiting scientist at the Royal Brompton and Harefield ...

other books by Barry Halliwell

Format:PaperbackDimensions:888 pages, 9.69 × 7.44 × 1.73 inPublished:March 15, 2007Publisher:Oxford University PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:019856869X

ISBN - 13:9780198568698

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Table of Contents

1. Oxygen is a toxic gas - an introductionto oxygen toxicity and reactive species2. The chemistry of free radicals and related 'reactive species'3. Antioxidant defences; Endogenous and Diet Derived4. Cellular responses to oxidative stress: adaptation, damage, repair, senescence and death5. Measurement of reactive species6. Reactive species can pose special problems needing special solutions. Some examples.7. Reactive species can be useful; some more examples8. Reactive species can be poisonous: their role in toxicology9. Reactive species and disease: fact, fiction or filibuster?10. Ageing, nutrition, disease, and therapy: A role for antioxidants?

Editorial Reviews

`'this publication conforms the needs of all groups of readers. The 3rd edition of the famous textbook of bioradical science is a remarkable book. In comparison with the 1st Edition it is considerably altered, expanded (936 vs 543 Pages) and updated ... I am not uncritical in my sincereadmiration of this unusual book ... If you consider buying a book on reactive oxygen species, this is number one' 'Cell Biology International