Fundamental Immunology by William E. PaulFundamental Immunology by William E. Paul

Fundamental Immunology

byWilliam E. PaulEditorWilliam E. Paul

Hardcover | December 19, 2012

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Fundamental Immunology

Seventh Edition

This standard-setting textbook has defined the field of immunology since 1984, and is now in its Seventh Edition continuing to deliver the detailed, authoritative, and timely coverage readers expect. This comprehensive, up-to-date text is ideal for graduate students, post-doctoral fellows, basic and clinical immunologists, microbiologists and infectious disease physicians, and any physician treating diseases in which immunologic mechanisms play a role.

Now full-color throughout the book's fully revised and updated content reflects the latest advances in the field. Current insights enhance readers' understanding of immune system function. The text's unique approach bridges the gap between basic immunology and the disease process. Extensive coverage of molecular biology explains the molecular dynamics underlying immune disorders and their treatment. Abundant illustrations and tables deliver essential information at a glance. Plus a convenient companion website features the fully searchable text with all references linked to PubMed.

Look inside and discover.../i>

• Fully revised and updated contentreflects the latest advances in the field.

• Current insightsenhance readers' understanding of immune system function

• Unique approachbridges the gap between basic immunology and the disease process.

• Extensive coverage of molecular biologyexplains the molecular dynamics underlying immune disorders and their treatment.

• Abundant illustrations and tablesdeliver essential information at a glance.


A convenient companion websitefeatures the fully searchable text with all references linked to PubMed.

Pick up your copy today!

Title:Fundamental ImmunologyFormat:HardcoverDimensions:1312 pages, 10.88 × 8.38 × 0.98 inPublished:December 19, 2012Publisher:Wolters KluwerLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:1451117833

ISBN - 13:9781451117837


Table of Contents

Section I. Introduction to Immunology

1 The Immune System

William E. Paul

2 History of Immunology

Steven Greenberg

Section II.Organization and Evolution of the Immune System

3 Lymphoid Tissues and Organs

Eitan M. Akirav, Noelia Alonso-Gonzalez, Lucy A. Truman, and Nancy H. Ruddle

4 Evolution of the Immune System

Martin F. Flajnik

Section III. Immunoglobulins and B Lymphocytes

5 Immunoglobulins: Structure and Function

Harry W. Schroeder

6 Immunoglobulins: Molecular Genetics

Edward E. Max and Sebastian Fugmann

7 Antigen-Antibody Reactions

Jay A. Berzofsky and Ira Berkower

8 B Lymphocyte Development

Richard R. Hardy

9 B Lymphocyte Receptors, Signaling Mechanisms, and Activation

Akanksha Chaturvedi, Angel Davey, Wanli Liu, Hae Won Sohn, and Susan K. Pierce

10 B Lymphocyte Responses

Michael McHeyzer-Williams

Section IV. T Lymphocytes

11 T Lymphocyte Receptors

Mark M. Davis

12 T Lymphocyte Signaling Mechanisms

Takashi Saito

13 T Lymphocyte Developmental Biology

Ellen V. Rothenberg and Ameya Champhekar

14 Peripheral T Lymphocyte Responses and Function

Marc K. Jenkins

Section V. The Intersection of Innate and Adaptive Immunity

15 The Innate Immune System

Luke A. J. O'Neill

16 Dendritic Cells

Michel C. Nussenzweig

17 Natural Killer Cells

Wayne M. Yokoyama

18 CD1d-restricted NKT Cells

Albert S. Bendelac

19 Macrophages and Phagocytosis

Siamon Gordon

20 Granulocytes and Mast Cells

Patrizia Scapini, Nicola Tamassia, Carlo Pucillo, and Marco A. Cassatella

21 The Major Histocompatibility Complex and its Proteins

David H. Margulies

22 Antigen Processing and Presentation

Ted H. Hansen and Paul A. Roche

Section VI. Induction, Regulation, and Effector Functions of the Immune Response

23 Immunogenicity and Antigen Structure

Jay A. Berzofsky

24 Fc Receptors and Their Role in Immune Regulation and Inflammation

Jeffrey V. Ravetch and Falk Nimmerjahn

25 Type I Cytokines and Interferons

Warren J. Leonard

26 Interleukin-1 Family Cytokines

Charles A. Dinarello and Mihai G. Netea

27 TNF-related Cytokines in Immunity

Carl F. Ware

28 Chemokines

Philip M. Murphy

29 Helper T Cell Differentiation and Plasticity

John J. O'Shea

30 Programmed Cell Death

Andrew L. Snow and Michael J. Lenardo

31 Immunological Memory

Shane Crotty, Susan M. Kaech, and Stephen P. Schoenberger

32 Immunological Tolerance

Pamela S. Ohashi

33 Regulatory/Suppressor T Cells

Ethan M. Shevach

34 Mucosal Immunity and Microbiome

Yasmine Belkaid

35 Neurophysiological Reflex Mechanisms in Immunology

Chavan and Kevin J. Tracey

36 Complement

B. Paul Morgan

37 Cell-mediated Cytotoxicity

Judy Lieberman

Section VII. Immunity to Infectious Agents

38 The Immune Response to Parasites

Thomas A. Wynne, David L. Sacks, Alan Sher, and Eleanor M. Riley

39 Immunity to Viruses

Hildegund C.J. Ertl

40 Immunity to Intracellular Bacteria

Anca Dorhoi, Stephen T. Reece, and Stefan H. E. Kaufmann

41 Immunity to Extracellular Bacteria

Moon H. Nahm and Jannet Katz

42 Immunology of HIV Infection

Bruce Walker

43 Vaccines

Ennio De Gregorio, Ugo D'Oro, Sylvie Bertholet, and Rino Rappuoli

Section VIII. Immunologic Mechanisms in Disease

44 Organ-Specific Autoimmunity

Ken T. Coppieters, Matthias G. von Herrath, and Dirk Homann

45 Allergy

Marsha Wills-Karp

46 Transplantation Immunology

Megan Sykes

47 Cancer Immunology

Hans Schreiber

48 Inborn Errors of Immunity

Jean-Laurent Casanova, Mary Ellen Conley, and Luigi D. Notarangelo