G Protein-Coupled Receptors in Health and Disease, Part B

Hardcover | October 23, 2009

byYa-xiong TaoEditorYa-xiong Tao

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G protein-coupled receptors GPCRs transduce signals from a diverse array of endogenous ligands, including ions, amino acids, nucleotides, lipids, peptides, and large glycoprotein hormones. They are also responsible for our sensing of exogenous stimuli, including photons and odorants. GPCRs regulate almost every aspect of our physiological functions. It is estimated that 40% to 50% of currently used therapeutic drugs target GPCRs directly or indirectly. Because the current drugs target only a small portion of the GPCRs, opportunities for targeting the remaining GPCRs is enormous. This volume reviews the latest developments in this rapidly advancing field. * This series provides a forum for discussion of new discoveries, approaches, and ideas * Contributions from leading scholars and industry experts * Reference guide for researchers involved in molecular biology and related fields

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G protein-coupled receptors GPCRs transduce signals from a diverse array of endogenous ligands, including ions, amino acids, nucleotides, lipids, peptides, and large glycoprotein hormones. They are also responsible for our sensing of exogenous stimuli, including photons and odorants. GPCRs regulate almost every aspect of our physiologi...

Dr. Ya-Xiong Tao is currently Associate Professor of Physiology at Auburn University College of Veterinary Medicine in Auburn, Alabama, USA. He has been working on several G protein-coupled receptors, including gonadotropin receptors regulating reproduction, and melanocortin receptors regulating energy and glucose homeostasis. He has p...

other books by Ya-xiong Tao

Format:HardcoverDimensions:192 pages, 9 × 6 × 0.98 inPublished:October 23, 2009Publisher:Academic PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0123747562

ISBN - 13:9780123747563

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Table of Contents

1. Diseased G protein-coupled receptors: An Introduction

Ya-Xiong Tao

2. GPR56 and its related diseases

Xianhua Piao and Ze Tian

3. GnRHR mutations and hypogonadotropic hypogonadism

Nicholas de Roux

4. LHR mutations and reproductive disorders

Deborah L. Segaloff

5. FSHR mutations and reproductive disorders

Ya-Xiong Tao and Deborah L. Segaloff

6. V2R mutations and nephrogenic diabetes insipidus

Daniel G. Bichet

7. Calcium-sensing receptor mutations

Geoffrey N. Hendy

8. Diseases caused by prostacyclin receptor mutations

John Hwa and Kathleen A Martin

Editorial Reviews

PRAISE FOR THE SERIES "Full of interest not only for the molecular biologist-for whom the numerous references will be invaluable-but will also appeal to a much wider circle of biologists, and in fact to all those who are concerned with the living cell."-British Medical Journal