Gene Action: A Historical Account

Hardcover | January 15, 2001

byWerner Maas

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This is the only book written by someone working in the field that deals with the history of gene action. As a college student, Werner Maas took a course in genetics in 1941 and wondered why so little was said about the biochemical action of genes in controlling the specific function of anorganism. Just at that time, biochemists and geneticists began to investigate jointly the basis of gene action, especially in microorganisms. Thus, Maas was able to witness firsthand the spectacular developments that led in the next twenty-five years to a clear picture of the action of genes. Thehistory of these remarkable discoveries is the core of this book. After 1965, building on insights gained from the work with microorganisms, studies of gene action turned to animals and plants and concentrated on processes not present in microorganisms, such as embryonic development, the role of genes in diseases, and the function of the nervous system. Becauseof the rapidity of technical advances made in handling genes, it has been possible to learn much about these complex processes. The last part of the book deals with these developments, which are ongoing parts of the history of gene action.

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This is the only book written by someone working in the field that deals with the history of gene action. As a college student, Werner Maas took a course in genetics in 1941 and wondered why so little was said about the biochemical action of genes in controlling the specific function of anorganism. Just at that time, biochemists and g...

Werner Maas is at New York University.

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Format:HardcoverPublished:January 15, 2001Publisher:Oxford University PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0195141318

ISBN - 13:9780195141313

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Table of Contents

PrefacePart I: The Classical Period, 1860-1940Prelude1. Overture: The Garden of Mendel2. Building a Scaffold: Genes Within ChromosomesPart II: One Gene-One Enzyme, 1900-1953Prelude3. The Dawn of the One Gene-One Enzyme Hypothesis during the Classical Period4. The Neurospora Era5. E. coli Enters the Field6. Biochemical Genetics in E. coli7. The Chemical Nature of GenesPart III: How Genes Determine Protein StructurePrelude8. Building a Theoretical Framework for Gene Action9. Biochemical Identification of Adaptors10. The Elusive Messenger11. Deciphering the CodePart IV: Regulation of Gene ActionPrelude12. Feedback Control of Biosynthetic Pathways13. Adaptive Enzymes14. The Operon ModelPart V: The Aftermath of the Operon ModelPrelude15 The Floodgates Open. Appendix/Further Readings

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BHM 76 #4, 12/02