Genetic Mapping and DNA Sequencing: GENETIC MAPPING & DNA SEQUENCI

Hardcover | August 27, 1996

EditorTerence Terry Speed, Michael WatermanbyT. P. Speed

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Genetics mapping, physical mapping and DNA sequencing are the three key components of the human and other genome projects. Statistics, mathematics and computing play important roles in all three, as well as in the uses to which the mapping and sequencing data are put. This volume edited by key researchers Mike Waterman and Terry Speed reviews recent progress in the area, with an emphasis on the theory and application of genetic mapping.

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Genetics mapping, physical mapping and DNA sequencing are the three key components of the human and other genome projects. Statistics, mathematics and computing play important roles in all three, as well as in the uses to which the mapping and sequencing data are put. This volume edited by key researchers Mike Waterman and Terry Speed ...

Format:HardcoverDimensions:232 pages, 9.25 × 6.1 × 0 inPublished:August 27, 1996Publisher:Springer New York

The following ISBNs are associated with this title:

ISBN - 10:0387948031

ISBN - 13:9780387948034

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Table of Contents

Contents: An introduction to recombination and linkage analysis.- Interference, heterogeneity, and disease gene mapping.- Estimating crossover frequencies and testing for numerical interference with highly polymorphic markers.- What is a genetic map function.- Haplogtyping algorithms.- Statistical aspects of trait mapping using a dense set of markers.- A comparative survey of non-adaptive pooling designs.- Parsing of genomic graffiti.- Improving DNA sequencing accuracy and throughput.- Assembly of shotgun sequencing data.