Genetics and Genomics of Neurobehavioral Disorders by Gene S. FischGenetics and Genomics of Neurobehavioral Disorders by Gene S. Fisch

Genetics and Genomics of Neurobehavioral Disorders

EditorGene S. Fisch

Paperback | November 9, 2010

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A clear and comprehensive account of how genetic abnormalities, neurobiology, and neuropsychology work together to manifest cognitive-behavioral dysfunction. The authors review the current status of research in autosomal disorders that produce cognitive-behavioral dysfunction and syndromal and nonsyndromal disorders that produce mental retardation. Comprehensive and up-to-date, Genetics and Genomics of Neurobehavioral Disorders integrates the molecular, genomic, neuropsychological, and neurobehavioral factors that produce learning disabilities and mental retardation into a coherent framework for the understanding and assessment of neurobehavioral disorders.

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Title:Genetics and Genomics of Neurobehavioral DisordersFormat:PaperbackDimensions:438 pages, 9.02 × 5.98 × 0 inPublished:November 9, 2010Publisher:Humana PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:1617373222

ISBN - 13:9781617373220

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Table of Contents

Part I. Introduction and OverviewThe Genetics and Genomics of Neurobehavioral Disorders: Historical Introduction and OverviewGene S. FischNeuroanatomical Considerations Specific to the Study of NeurogeneticsAlbert M. Galaburda and J. Eric SchmittModeling Cognitive Disorders: From Genes to TherapiesRui M. Costa, Ype Elgersma, and Alcino J. SilvaWhat Can the Study of Behavioral Phenotypes Teach Us About the Pathway from Genes to Behavior?Jonathan FlintPart II. Autosomal Disorders and Neurobehavioral DysfunctionThe Central Nervous System in Neurofibromatosis Type 1Nancy Ratner and Kathryn NorthPrader-Willi and Angelman Syndromes: Cognitive and Behavioral PhenotypesElisabeth M. Dykens and Suzanne B. CassidyTuberous SclerosisJulian R. Sampson and Julia C. LewisBehavioral Phenotype in Velo-Cardio-Facial SyndromeKieran C. MurphyWilliams-Beuren SyndromeMònica Bayés and Luis A. Pérez JuradoBehavioral Phenotype in Myotonic Dystrophy (Steinert's Disease)Jean SteyaertPart III. X-Linked Nonsyndromal Disorders and Neurobehavioral DysfunctionGenetics of X-Linked Mental RetardationJamel Chelly and Ben C. J. HamelNonsyndromal Mental Retardation Associated with the FRAXE Fragile Site and the FMR2 GeneJozef Gécz and Gene S. FischPart IV. X-Linked Syndromal Disorders and Neurobehavioral DysfunctionATR-X SyndromeTakahito Wada and Richard J. GibbonsThe Fragile X Syndrome and the Fragile X MutationMark C. Hirst and Gene S. FischRett Syndrome: Clinical-Molecular CorrelatesAlan K. Percy, Joanna Dragich, and N. Carolyn SchanenIndex

Editorial Reviews

"this book brings together research from neuroscience, genetics, and psychology in a concise and unique way. This type of synthesis is sorely needed as we struggle to understand the complexities of human brain function and dysfunction. It is a valuable contribution to these fields as is, and it is exciting to speculate what future editions will contain. "-Doody's Health Sciences Book Review Journal"...Gene Fisch has edited a remarkable volume...I highly recommend this book for clinicians, researchers, and students interested in neurodevelopmental disorders." - Human Genetics"...a comprehensive and highly accessible review of this enormously interesting body of work...a highly readable and thought-provoking volume." - J. AM. ACAD. CHILD ADOLESC. PSYCHIATRY"...a useful update on behavioral phenotypes for which the neurobiological substrates are beginning to reveal their secrets." - Association for Child Psychology"...a useful update on behavioral phenotypes for which the neurobiological substrates are beginning to reveal their secrets." - Journal of Child Psychology and Psychiatry