Genetics of Obesity Syndromes

Hardcover | September 12, 2008

byPhilip R. Beales, Peter R. Scambler

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Obesity is one of the most important contributing factors to disease throughout the world and is an area of great current interest among researchers and clinicians. The genetics of common obesity is complex, and an important thread through this labyrinth is the study of genetic syndromes inwhich obesity is a major component. By examining the genetic mechanisms of obesity in these syndromes, the authors will shed new light on the genetics of common obesity. This is the first book on this important and exciting new area and addreses both the molecular and clinical features of theobesity syndromes, providing hard-core information for researchers and practical guidelines for clinicians caring for obese patients. The book is divided into three sections: the first covers approaches for assessing and investigating the obese individual; the second describes nondysmorphic, monogenic forms of obesity; and the third documents key, multisystem obesity syndromes with various genetic etiologies. It is as much areference book as it is a manual and will appeal to clinical geneticists, obesity researchers, endocrinologists, nutritionists, and medical biologists.

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From the Publisher

Obesity is one of the most important contributing factors to disease throughout the world and is an area of great current interest among researchers and clinicians. The genetics of common obesity is complex, and an important thread through this labyrinth is the study of genetic syndromes inwhich obesity is a major component. By examini...

Philip R. Beales is in the Molecular Medicine Unit, Institute of Child Health at Great Ormond Street Hospital for Children, London.

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Format:HardcoverDimensions:304 pages, 6.42 × 9.21 × 0.91 inPublished:September 12, 2008Publisher:Oxford University PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0195300165

ISBN - 13:9780195300161

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Table of Contents

Section I1. Phillip L. Beales, Sadaf Farooqi: Introduction2. Sadaf Farooqi: A Practical Guide to the Clinical Assessment and Investigation of ObesitySection II: Non-Syndromic Obesity3. Sadaf Farooqi, Stephen O'Rahilly: Leptin and Leptin Receptor Deficiency4. Heike Krude: Pro-opiomelanocortin Deficiency5. Robert S. Jackson: Prohormone Convertase6. Sadaf Farooqi, Stephen O'Rahilly: Melanocortin 4 Receptor DeficiencySection III: Syndromic Obesity7. Louise C. Wilson: Albrights Hereditary Osteodystrophy, Pseudoparathyroidism and Other GNAS Associated Syndromes8. Gayle B. Collin, Jan D. Marshall, Jurgen K. Naggert, Patsy M. Nishina: The Clinical and Molecular Genetics of Alstrom Syndrom9. Alison Ross, Phillip L. Beales, and Josephine Hill: The Clinical, Molecular, and Functional Genetics of Bardet-Biedl Syndrome10. Joanna Crawford, Michael Partington, Mark Corbett, Karen Lower, Jozef Gecz: The Borjeson-Forssman-Lehmann Syndrome11. Kate E. Chandler, F.D.C. Manson: The Cohen Syndrome12. Rachel Wevrick: Prader-Willi Syndrome13. Phillip L. Beales, Raoul Hennekam: Syndromes with Obesity