This is a new edition in the Cellular and Molecular Neurobiology series. The vast majority of cells in the nervous system are glial cells. During development, these cells provide growth factors that stimulate the proliferation, migration and survival of neurones and their precursors, andpromote and guide axonal growth. In the mature nervous system, glial cells provide insulating myelin sheathe around axons and provide metabolic and structural support for neurones. Glial cells also have a major influence on the local response to injury of the central nerve tract and the peripheralnervous system, either promoting, or inhibiting, axonal regrowth and recovery of lost function. This book provides a comprehensive, state-of-the-art overview of research into the development, function and malfunction of glial cells. It offers a compelling insight into how basic research throwslight onto diseases and disorders and points the way towards treatments. Teams of internationally renowned experts, all active in research, have contributed chapters.