Glutamate and Addiction by Barbara H. HermanGlutamate and Addiction by Barbara H. Herman

Glutamate and Addiction

EditorBarbara H. Herman

Paperback | November 9, 2010

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In Glutamate and Addiction, world-renowned scientific experts critically review all of the evidence for the role of glutamatergic systems in opiate, stimulant, and alcohol addiction. Using a variety of pharmacological, biochemical, genetic, and brain imaging techniques, these investigators show precisely how glutamate affects such addictions and how modifying certain elements of the glutamatergic system appear to alleviate particular components of addiction. Their survey takes in both clinical approaches using medications that influence glutamate and cutting-edge preclinical approaches that manipulate specific subtypes of glutamate receptors or specific substrates of the "glutamate cascade" to determine their roles in various addictive states.
Title:Glutamate and AddictionFormat:PaperbackDimensions:458 pagesPublished:November 9, 2010Publisher:Humana PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:161737234X

ISBN - 13:9781617372346

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Table of Contents

I. Introduction: Physiology and Pharmacology of GlutamatePhilip H. Sheridan, Forrest F. Weight, and Barbara H. Herman, Section EditorsMolecular Pharmacology and Physiology of Glutamate ReceptorsKarin Borges and Raymond DingledinePharmacology of Glutamate ReceptorsJeffrey M. Witkin, Rafal Kaminski, and Michael A. RogawskiGlutamate and NeurotoxicityB. Joy Snider and Dennis W. ChoiMaturational Regulation of Glutamate Receptors and Their Role in NeuroplasticityRussell M. Sanchez and Frances E. JensenRole of the NMDA Receptor in Neuronal Apoptosis and HIV-Associated DementiaMarcus Kaul and Stuart A. LiptonII. Glutamate: Stimulant Drugs of Abuse (Cocaine, Amphetamine, Methamphetamine)Jerry Frankenheim and Barbara H. Herman, Section EditorsRole of Glutamate and Nitric Oxide in the Acquisition and Expression of Cocaine-Induced Conditioned Increases in Locomotor ActivityAgu Pert, Robert M. Post, and Susan R. B. WeissInteractions of Dopamine, Glutamate, and GABA Systems in Mediating Amphetamine- and Cocaine-Induced Stereotypy and Behavioral SensitizationRalph Karler, David K. Thai, and Larry D. CalderAddiction and Glutamate-Dependent PlasticityMarina E. WolfGlutamate and Dopamine Interactions in the Motive Circuit: Implications for Craving, David A. Baker, Jennifer L. Cornish, and Peter W. KalivasGlutamate Cascade from Metabotropic Glutamate Receptors to Gene Expression in Striatal Neurons: Implications for Psychostimulant Dependence and MedicationJohn Q. Wang, Limin Mao, and Yuen-Sum LauGlutamate Neurotransmission in the Course of Cocaine AddictionLuigi PulvirentiGlutamate and the Self-Administration of Psychomotor-Stimulant DrugsPaul Vezina and Nobuyoshi SutoRoles of Glutamate, Nitric Oxide, Oxidative Stress, and Apoptosis in the Neurotoxicity of MethamphetamineJean Lud CadetMethamphetamine Toxicity: Roles for Glutamate, Oxidative Processes, and Metabolic StressKristan B. Burrows and Bryan K. YamamotoNitric Oxide-Dependent Processes in the Action of PsychostimulantsYossef Itzhak, Julio L. Martin, and Syed F. AliEffects of Novel NMDA/Glycine-Site Antagonists on the Blockade of Cocaine-Induced Behavioral Toxicity in MiceRae R. Matsumoto and Buddy PouwClinical Studies Using NMDA Receptor Antagonists in Cocaine and Opioid DependenceAdam Bisaga and Marian W. FischmanThe Role of mGluR5 in the Effects of Cocaine: Implications for Medication DevelopmentMark P. Epping-JordanIII. Glutamate and Opiate Drugs (Heroin) of AbuseBarbara H. Herman and Jerry Frankenheim, Section EditorsRole of the Glutamatergic System in Opioid Tolerance and Dependence: Effects of NMDA Receptor AntagonistsJianren MaoThe Role of NMDA Receptors in Opiate Tolerance, Sensitization, and Physical Dependence: A Review of the Research, A Cellular Model, and Implications for the Treatment of Pain and AddictionKeith A. TrujilloModification of Conditioned Reward by N-Methyl-d-aspartate Receptor AntagonistsPiotr PopikMorphine Withdrawal as a State of Glutamate Hyperactivity: The Effects of Glutamate Receptor Subtype Ligands on Morphine Withdrawal SymptomsKurt RasmussenIV. Glutamate and Alcohol Abuse and AlcoholismForrest F. Weight and Raye Z. Litten, Section EditorsAlcohol Actions on Glutamate ReceptorsRobert W. PeoplesGlutamate and Alcohol-Induced NeurotoxicityFulton T. Crews, Joseph G. Rudolph, and L. Judson ChandlerRole of Glutamate in Alcohol Withdrawal KindlingHoward C. Becker and Nicole RedmondAlcohol and Glutamate Neurotransmission in Humans: Implications for Reward, Dependence, and TreatmentJohn H. Krystal, Ismene L. Petrakis, D. Cyril D'Souza, Graeme Mason, and Louis TrevisanMechanism of Action of Acamprosate Focusing on the Glutamatergic SystemW. Zieglgänsberger, G. Rammes, R. Spanagel, W. Danysz, and Ch. ParsonsThe NMDA/Nitric Oxide Synthase Cascade in Opioid Analgesia and ToleranceGavril W. Pasternak and Yuri KolesnikovOverview of Clinical Studies for AcamprosateAdriaan S. PotgieterIndex

Editorial Reviews

"Illuminating, authoritative, and forward looking, Glutamate and Addiction clarifies for the first time the relationship between glutamatergic systems and addiction investigations of many of today's emerging therapeutics for addictive disorders." -Biomedicine and Pharmacotherapy