Gluten Related Disorders: People Shall not Live on Bread Alone by Carlo CatassiGluten Related Disorders: People Shall not Live on Bread Alone by Carlo Catassi

Gluten Related Disorders: People Shall not Live on Bread Alone

Guest editorCarlo Catassi, Alessio Fasano

Paperback | April 28, 2017

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Once upon a time, gluten was not part of the human diet, and therefore, there were no gluten-related disorders. With the advent of agriculture 10,000 years ago, the introduction of gluten-containing grains in the human diet created conditions for human diseases related to gluten exposure. These diseases, including celiac disease, non-celiac gluten sensitivity, and wheat allergy, have distinct pathophysiological mechanisms, serological markers, and long-term treatments, but similar, often overlapping clinical presentations. Though current research strives to clarify the boundaries between these entities, their differences can be difficult to distinguish.
For a very long time, awareness of these disorders has been limited and, therefore, the epidemiology of gluten-related disorders has been a “work in progress”. New epidemiological studies have revealed that gluten-related disorders are not limited to European regions; rather, they are present worldwide.
After centuries of neglected attention to celiac disease and other forms of gluten reaction, now we are observing another interesting phenomenon that is generating great confusion among health care professionals. Nearly 25% of Americans (many more than the projected 3 million celiac disease (CD) patients in the U.S.) are reducing or cutting gluten from their diets. This remarkable trend in the general population reflects the misconception that gluten can be harmful for everybody and, therefore, should be avoided to stay healthy, to lose weight, or even to prevent severe diseases.
This Special Issue Book of Nutrients contains contributions from leading experts in the field of gluten-related disorders that will help dissipate this confusion by sharing their evidence-based science, which will help the reader to distinguish facts from fantasies.

Title:Gluten Related Disorders: People Shall not Live on Bread AloneFormat:PaperbackProduct dimensions:252 pages, 9.61 × 6.69 × 0.68 inShipping dimensions:9.61 × 6.69 × 0.68 inPublished:April 28, 2017Publisher:MDPI AGLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:3038423564

ISBN - 13:9783038423560


Table of Contents

1) Central America in Transition: From Maize to Wheat Challenges and Opportunities
2) Intestinal Microbiota and Celiac Disease: Cause, Consequence or Co-Evolution?
3) Effect of Gliadin on Permeability of Intestinal Biopsy Explants from Celiac Disease Patients and Patients with Non-Celiac Gluten Sensitivity
4) The Role of Gluten in Celiac Disease and Type 1 Diabetes
5) Increased Intraepithelial Vα24 Invariant NKT Cells in the Celiac Duodenum
6) Gliadin-Specific T-Cells Mobilized in the Peripheral Blood of Coeliac Patients by Short Oral Gluten Challenge: Clinical Applications
7) DQ2, DQ7 and DQ8 Distribution and Clinical Manifestations in Celiac Cases and Their First-Degree Relatives
8) The Spectrum of Differences between Childhood and Adulthood Celiac Disease
9) Seronegative Celiac Disease and Immunoglobulin Deficiency: Where to Look in the Submerged Iceberg?
10) Non-Celiac Gluten Sensitivity Has Narrowed the Spectrum of Irritable Bowel Syndrome: A Double- Blind Randomized Placebo-Controlled Trial
11) Cutaneous Manifestations of Non-Celiac Gluten Sensitivity: Clinical Histological and
Immunopathological Features
12) Gluten Psychosis: Confirmation of a New Clinical Entity
13) Recognising and Managing Refractory Coeliac Disease: A Tertiary Centre Experience
14) The Effects of Reduced Gluten Barley Diet on Humoral and Cell-Mediated Systemic Immune  Responses of Gluten-Sensitive Rhesus Macaques
15) Sourdough Fermentation of Wheat Flour does not Prevent the Interaction of Transglutaminase 2
with α2-Gliadin or Gluten
16) Self-Reported Prevalence of Symptomatic Adverse Reactions to Gluten and Adherence to Gluten-
Free Diet in an Adult Mexican Population
17) Bones of Contention: Bone Mineral Density Recovery in Celiac Disease—A Systematic Review
18) Analysis of Body Composition and Food Habits of Spanish Celiac Women
19) Diagnosis of Non-Celiac Gluten Sensitivity (NCGS): The Salerno Experts’ Criteria