Hallelujah Moments: Tales of Drug Discovery

Hardcover | January 28, 2014

byEugene H. Cordes

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Drug discovery in the pharmaceutical industry has important consequences for the health and wellbeing of people everywhere. However, the general public knows little about the paths through which basic research findings are translated into products that protect or restore human health: theroute from the laboratory bench to the bedside. In Hallelujah Moments, Eugene Cordes reveals how some of the most important and influential drugs have been brought into the practice of clinical medicine through the wit and determination of scientists in academia and industry. He shares his firsthandknowledge of the drug-discovery world, having spent a long and distinguished career in both the academic and industrial settings. These tales are "adventure stories," and they trace the route of important drugs like Januvia, Primaxin, Capoten, and Zocor from concept to the clinic. Cordes shows us the dynamic and critical thinking needed to create a drug that meets important health needs. These are human stories of imagination,risk-taking, problem-solving, and perseverance. Written accessibly for a non-scientist audience, Hallelujah Moments provides insights into the fascinating world of drug discovery like never before.

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From the Publisher

Drug discovery in the pharmaceutical industry has important consequences for the health and wellbeing of people everywhere. However, the general public knows little about the paths through which basic research findings are translated into products that protect or restore human health: theroute from the laboratory bench to the bedside. ...

Dr. Eugene Cordes has served as Vice President of Biochemistry and Molecular Biology in the Research Laboratories of Merck and Company and as President of Research and Development at Sterling Winthrop Pharmaceuticals Inc. In addition he has been a professor at Indiana University and the University of Michigan. He is the author of The T...

other books by Eugene H. Cordes

Format:HardcoverDimensions:264 pages, 9.25 × 6.12 × 0.98 inPublished:January 28, 2014Publisher:Oxford University PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0199337144

ISBN - 13:9780199337149

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Table of Contents

1. Seduced by drug discovery2. The small molecules of life3. Proteins: molecular wonders in three dimensions4. Proteins perform multiple functions: enzymes, receptors, ion channels5. Drug discovery and development: the road from an idea to promoting human health6. Finasteride: the Gary and Jerry show7. Basic research, snake venoms, and ACE inhibitors: Ondetti, Cushman, and Patchett8. Statins: protection against heart attacks and strokes9. The perils of Primaxin10. Avermectins: molecules of life battle parasites11. Fludalanine: nice try but no hallelujah12. Diabetes Breakthrough: Januvia and Janumet