Handbook of Downstream Processing by E. GoldbergHandbook of Downstream Processing by E. Goldberg

Handbook of Downstream Processing

byE. Goldberg

Paperback | October 1, 2011

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The last two decades have witnessed a phenomenal growth in the field of genetic or biochemical engineering, and a variety of products has been developed and marketed through the manipulation and growth of different types of microorganisms and the recovery and purification of the associated products.
Title:Handbook of Downstream ProcessingFormat:PaperbackDimensions:720 pagesPublished:October 1, 2011Publisher:Springer-Verlag/Sci-Tech/TradeLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:9401071985

ISBN - 13:9789401071987

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Table of Contents

Preface. Lysing. Filtration. Pharmaceutical applications of liquid-liquid extractions. Affinity adsorption. Membrane separations in downstream processing. Electrodialysis. Large-scale column chromatography: a GMP manufacturing perspective. Product recovery and purification via precipitation and crystallization. Lyophilization. Drying in the pharmaceutical and biotech fields. Sterilization in the pharmaceutical and biotechnology industries. Pharmaceutical packaging operations. Clean-in-place and sterilize-in-place systems. Controls and automation for biotech and pharmaceutical industries. Agitation in fermenters and bioreactors. Distillation in the pharmaceutical industry. High purity water. The facility design process. Clean room testing and certification. Regulatory considerations. Validation. Project execution for the design and construction of a biotech facility. Bulk pharmaceutical and biopharmaceutical plant design considerations. Optimization of protein recovery using computer-aided process design tools. Off-site construction: application to the pharmaceutical and biotech industries. Wastewater treatment in the pharmaceutical industry. References. Index.

Editorial Reviews

`... the book offers a great deal of useful information for readers.' Angewandte Chemie