Hemoglobin Disorders: Molecular Methods and Protocols by Ronald L. NagelHemoglobin Disorders: Molecular Methods and Protocols by Ronald L. Nagel

Hemoglobin Disorders: Molecular Methods and Protocols

EditorRonald L. Nagel

Paperback | November 9, 2010

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A collection of readily reproducible experimental and clinical techniques for studying the molecular basis of hemoglobin disorders. These step-by-step methods utilize a wide variety of the latest analytical techniques, including x-ray crystallography, high performance liquid chromatography, electrophoresis, and nuclear magnetic resonance. Additional methods are offered for prenatal diagnostic analysis, the DNA diagnosis of hemoglobin mutations, hemoglobin fluorescence, and the semisynthesis of hemoglobin.
Title:Hemoglobin Disorders: Molecular Methods and ProtocolsFormat:PaperbackDimensions:320 pages, 9.02 × 5.98 × 0 inPublished:November 9, 2010Publisher:Humana PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:1617372781

ISBN - 13:9781617372780

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Table of Contents

X-ray Crystallography of HemoglobinsMartin K. Safo and Donald J. AbrahamAnalysis of Hemoglobins and Globin Chains by High-Performance Liquid ChromatographyHenri WajcmanPurification and Molecular Analysis of Hemoglobin by High-Performance Liquid ChromatograpyBelur N. Manjula and Seetharama A. AcharyaOxygen Equilibrium Measurements of Human Red Blood CellsJean Kister and Henri WajcmanMeasurement of Rate Constants for Reactions of O2, CO, and NO with HemoglobinJohn S. Olson, Erin W. Foley, David H. Maillett, and Eden V. PasterElectrophoretic Methods for Study of HemoglobinsHenri WajcmanDNA Diagnosis of Hemoglobin MutationsJohn M. Old. Methods for Analysis of Prenatal Diagnosis, John M. OldHemoglobin FluorescenceRhoda Elison HirschNucleation and Crystal Growth of Hemoglobins: The Case of HbCPeter G. Vekilov, Angela Feeling-Taylor, and Rhoda Elison HirschSemisynthesis of HemoglobinSeetharama A. Acharya and Sonati Srinivasulub-Globin-like Gene Cluster Haplotypes in HemoglobinopathiesShanmugakonar Muralitharan, Rajagopal Krishnamoorthy, and Ronald L. NagelTransgenic Mice and HemoglobinopathiesMary E. Fabry, Eric E. Bouhassira, Sandra M. Suzuka, and Ronald L. NagelRecombinant Single Globin-Chain Expression and PurificationKazuhiko AdachiNuclear Magnetic Resonance of HemoglobinsJonathan A. Lukin and Chien HoSolubility Measurement of the Sickle PolymerMary E. Fabry, Seetharama A. Acharya, Sandra M. Suzuka, and Ronald L. NagelIndex

Editorial Reviews

"...the book is a very good practical volume for those interested in further clinical and experimental studies of hemoglobin disorders." - Biomedical Chromatography