High Pressure Effects in Biophysics and Enzymology by John L. Markley

High Pressure Effects in Biophysics and Enzymology

EditorJohn L. Markley, Dexter B. Northrop, Catherine A. Royer

Hardcover | April 30, 1999

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High Pressure Effects in Molecular Biophysics and Enzymology is designed to acquaint biochemists, biophysicists, and graduate students with advances in the application of high pressure in connection with spectroscopy as a research tool in the study of biomolecules. The 23 chapters written byleading authorities present an overview of current approaches to the use of high pressure in research on enzyme kinetics, protein folding and structure, lipid bilayer structure and organization, lipid-protein interaction, and DNA structure. This important, timely volume is the first devotedexclusively to high-pressure effects in biochemistry and will be the definitive reference in its subject for the next several years.

About The Author

John Markley, Dexter Northrop, and Catherine A. Royer are all at the University of Wisconsin-Madison.
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Title:High Pressure Effects in Biophysics and EnzymologyFormat:HardcoverDimensions:400 pages, 9.57 × 6.46 × 1.1 inPublished:April 30, 1999Publisher:Oxford University Press

The following ISBNs are associated with this title:

ISBN - 10:019509722X

ISBN - 13:9780195097221

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Table of Contents

Contributors1. Gregorio Weber: Resolution of the Ambiguity of van't Hoff Plots by the Effect of Pressure on the Equilibrum2. H. G. Drickamer: Pressure-Tuning Spectroscopy: A Tool for Investigating Molecular Interactions3. Kenneth E. Prehoda and John L. Markley: Use of Partial Molar Volumes of Model Compounds in the Interpretation of High-Pressure Effects on Proteins4. Karel Heremans, Koen Goossens, and Laszlo Smeller: Pressure-Tuning Spectroscopy of Proteins:Fourier Transform Infrared Studies in the Diamond Anvil Cell5. Maurice R. Eftink and Glen D. Ramsay: Temerature- and Pressure-Induced Unfolding of a Mutant of Staphylococcal Nuclease A6. Gediminas J. A. Vidugiris, Raj Thomas, and Catherine A. Royer: Pressure-Jump Relaxation Kinetics of Unfolding and Refolding Transitions of Staphylococcal Nuclease and Proline Isomerization Mutants7. Yoshihiro Taniguchi and Naohiro Takeda: High-Pressure FTIR Studies of the Secondary Structure of Proteins8. Xiangdong Peng et al.: High-Pressure NMR Studies of the Dissociation of Arc Repressor and the Cold Denaturation of Ribonulease A9. Mauro Villas-Boas et al.: Exploring Structural, Functional, and Kinetic Aspects of Nucleic Acid-Protein Complexes with Pressure: Nucleosomes and RNA Polymerase10. Jerson L. Silva, Andrea T. Da Poian, and Debora Foguel: Pressure and Cold Denaturation of Proteins, Protein-DNA Complexes, and Viruses11. Robert B. Macgregor Jr., John Q. Wu, and Reza Najaf-Zadeh: Sequence, Salt, Charge and the Stability of DNA at High Pressure12. Gaston Hui Bon Hoa et al.: Application of Pressure Relaxation to the Study of Substrate Binding to Cytochrome P-450CAM versus Temperature, Pressure, and Viscosity13. Isao Morishima: Pressure Effects on the Ligand-Binding Kinetics for Hemo proteins and Their Site-Directed Mutants14. Claude Balny: Transient Enzyme Kinetics at High Pressure15. Dexter Northrup: Steady-State Enzyme Kinetics at High Pressure16. Jason L. Johnson and Gregory D. Reinhart: Effects of High Pressure on the Allosteric Properties of Phosphofructokinase from Escherichia coli17. Patrick T. T. Wong: Correlation Field Splitting of Chain Vibrations: Structure and Dynamics in Lipid Bilayers and Biomembranes18. Roland Winter et al.: High-Pressure Effects on the Structure of Phase Behavior of Model Membrane Systems19. Parkson Lee-Gau Chong: Membrane-Free Volume Variation with Bulky Lipid Concentration by Regular Distribution: A Functionally Important Membrane Property Explored by Pressure Studies of Phosphatidylcholine Bilayers20. Ana Jonas et al.: NMR Studies of the Order and Dynamics of Dipalmitoylphosphatidylcholine Bilayers as a Function of Pressure21. Suzanne F. Scarlata: Effects of Increased Viscosity on the Function of Integral Membrane Proteins22. Horst Ludwig, Wilhelm Scigalla, and Bernd Sojka: Pressure- and Temperature-Induced Inactivation of Microorganisms23. Stephen G. Sligar, Clifford R. Robinson, and Mark A. McLean: Osmotic and Hydrostatic Pressure as Tools to Study Molecular RecognitionIndex

From Our Editors

This book presents an overview of current research on pressure perturbations on enzyme kinetics, protein folding and structure, lipid bilayer structure and organization, lipid-protein interactions, DNA structure, and protein-ligand interactions.

Editorial Reviews

"This volume is a result of the Steenbock Symposium on High-Pressure Effects in Molecular Biophysics and Enzymology . . . [It] is not an introduction to applications of pressure perturbation in biology. Rather, its purpose is to present the state of the art in this field. . . . As such, itwill serve as a valuable reference for investigators who are either working in this field or who wish to become familiar with the important issues in pressure effects on biological systems, and ways to use pressure as a tool in biophysics. The 23 articles discuss the effects of pressure onbiological systems, the interpretation of thermodynamic parameters derived from pressure perturbation, and physical chemical techniques that have been successfully combined with high-pressure perturbation. . . . This volume represents an important contribution to the literature covering methods andapplications of high-pressure perturbation in biophysics."--The Quarterly Review of Biology