Histology of the Nervous System of Man and Vertebrates: Two-Volume Set

Hardcover | October 1, 1984

byS. Ramon y CajalTranslated byNeely Swanson, Larry Swanson

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With the research summarized in this monumental two volume treatise, Santiago Ramon y Cajal founded modern neuroscience and thus joined Darwin and Pasteur as the leading biologists of the 19th century. Starting around 1887, Cajal refined a neurological staining method developed almost 15 yearsearlier by the Italian histologist Camillo Golgi, and applied it first to relatively orderly parts of the nervous systems like the cerebellum, spinal cord, and retina. The conclusions he drew about the organization of neural circuits were, however, diametrically opposed to those advocated by Golgi,spurring an acrimonious debate that lasted well after the two shared the Nobel Prize in 1906. Early on, Cajal concluded that neural circuits are made up of individual units or nerve cells and interact by way of contact, whereas Golgi believed that such circuits are formed by a reticulum or net ofcontiguous nerve cells. Cajal was the first to see how neurons interact in the brain, laying the foundation for what came to be known as the neuron doctrine. His second great contribution was the ability to predict the direction of information flow in neural circuits based strictly on morphologicalcriteria: dendrites and soma form the input side of a neuron while the axon forms its output side. This became known as the functional polarity hypothesis. Using these two foundation stones, Cajal went on to analyze systematically all parts of the mammalian nervous system, along with selected parts in all classes of vertebrates. A synthesis of that work, this volume, which is accompanied by over 1,000 original illustrations, is based almost entirelyon personal observation and offers a wealth of factual, historical, and theoretical information.

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With the research summarized in this monumental two volume treatise, Santiago Ramon y Cajal founded modern neuroscience and thus joined Darwin and Pasteur as the leading biologists of the 19th century. Starting around 1887, Cajal refined a neurological staining method developed almost 15 yearsearlier by the Italian histologist Camillo ...

S. Ramon y Cajal is at University of Madrid. Neely Swanson is at University of Southern California. Larry Swanson is at University of Southern California.

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Format:HardcoverDimensions:1672 pages, 7.91 × 11.54 × 4.88 inPublished:October 1, 1984Publisher:Oxford University Press

The following ISBNs are associated with this title:

ISBN - 10:0195074017

ISBN - 13:9780195074017

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Table of Contents

VOLUME IGeneral Principles1. Basic Plan of the Nervous System2. Research Methods and Major Results3. Neurons: Size and General Morphology4. The Connections and Comparative Morphology of Neurons5. Functional Implications of Neuronal Morphology and Connections6. Fine Structure of the Neuron7. Variations in the Structure and Shape of Neurons Under Normal and Pathological Conditions and the Functional Implications of Such Variations8. Neuroglia9. Nerve FibersSpinal Cord10. The Spinal Cord11. Structure of Spinal White Matter12. Structure of the Gray Matter13. Commissural and Funicular Neurons14. Arrangement of Funicular Neurons in Various Parts of the Gray Matter15. Extraspinal Neurons with an Axon in the Cord16. The Peripheral Endings of Spinal Ganglion Cells17. The Central Process of Spinal Ganglion Cells18. Glia of the Spinal Gray Matter19. Functional Implications Arising From New Concepts About the Structure of the Spinal Cord20. Comparative Histology of the Spinal Cord21. Histogenesis of the Spinal Cord and Spinal GangliaMedulla and Pons22. The Medulla23. Internal Structure of the Medulla24. General Features of the Medulla Hypoglossal Nucleus25. The Accessory Spinal or XIth Cranial Nerve26. The Vagus and Glossopharyngeal or IXth and Xth Cranial Nerves27. The Vestibulocochlear Nerve: Vestibular Nerve28. The Vestibulocochlear Nerve: Cochlear Branch or Nerve29. The Facial or VIIth Cranial Nerve30. The Abducens or VIth Cranial Nerve31. The Trigeminal or Vth Cranial Nerve32. Neuronal Pathways of the Medulla and Associated Nuclei33. Medullary Extension of the Spinal Ventral Funiculus34. The Lateral Funiculus and Its Medullary Nuclei35. Intrinsic Pathways and Nuclei of the Medulla36. The PonsVOLUME IIThe Cerebellum1. The Cerebellar Cortex2. The Granular Layer3. Cerebellar White Matter and Glia4. Comparative Histology of the Cerebellar Cortex5. Cerebellar Histogenesis6. Deep Cerebellar Nuclei7. Cerebellar PedunclesThe Midbrain8. The Inferior Colliculus9. The Superior Colliculus10. The Optic Lobe of Lower Vertebrates11. The Tegmental or Intermediate Region of the Midbrain12. Tegmental Region (Continued)13. Ventral Regions of the MidbrainDiencephalon14. The Thalamus and Its Nuclei15. Visual Apparatus Retina or Receptor Organ for Visual Stimuli16. The Retina (Continued): The Retina of Other Vertebrates17. The Optic Nerve, Chiasm, and Tract18. The Lateral Geniculate Body and Pulvinar19. Thalamus (Continued)20. Thalamus (Continued): Medial Nuclei21. Hypothalamic Region and Its Nuclei22. Diencephalon (Continued)23. The Corpus StriatumCerebral Cortex24. General Structure of the Cerebral Cortex25. Regions of the Cerebral Cortex: Visual Cortex26. Auditory Cortex27. Motor or Somatosensory-Motor Cortex28. Olfactory Apparatus: Olfactory Mucosa and Olfactory Bulb or First-Order Olfactory Centers29. Secondary and Tertiary Olfactory Centers30. Pathways From the Temporal Olfactory Cortex31. Fourth-Order Olfactory Areas Ammon's Horn and the Dentate Gyrus32. Afferent and Efferent Projections of Ammon's Horn and the Dentate Gyrus33. Cingulate Cortex and Cingulum34. Comparative Structure of the Cerebral Cortex35. Histogenesis of the Cerebral Cortex36. Structure-Function Relationships in the CortexAutonomic Nervous System37. Autonomic Nervous System

Editorial Reviews

"It is a book in which to gain an intimate acquaintance with an extraordinarily gifted, dedicated and original mind whose total involvement with the discovery, details and development of neurohistology and, perhaps most importantly, its functional interpretation, is communicated with clarityand excitement."--Trends in Neurosciences