How Genes Influence Behavior by Jonathan Flint

How Genes Influence Behavior

byJonathan Flint, Ralph J. Greenspan, Kenneth S. Kendler

Paperback | February 1, 2010

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How important are genetic influences on behavior?How many genes influence an individual behavior, and how much influence does a single gene have? How do genes interact with the environment to influence the development of behavioral traits?What are the differences between humans and 'simpler' organisms when it comes to the genetic control of behavior? How Genes Influence Behavior is a unique introduction to behavioral genetics, which combines conceptual rigor with accessibility to answer questions such as these - answers that carry important implications for the nature of who we are. Offering unparalleled insights into how behavioural genetics is probed through real-world research, it considers evidence from humans and the major model organisms of mouse, fruit-fly and nematode worm to demonstrate how much of our current understanding of the genetic basis of human behavior stemsfrom our exploration of other animals. Further, it uses these studies to connect the key themes of the book - the nature of gene action, and the inter-relationship of genetic and environmental influences on behaviour - across organisms, highlighting key commonalities and differences.The book also shows the major impact that neurobiology is having on our understanding of the field, to give a true depiction of behavioral genetics in the 21st century. However, care is taken throughout not to overwhelm the reader with scientific detail. Instead, the authors make the book fun toread without sacrificing accuracy or devaluing the complexity of the subject matter: they 'personalize' the science, mixing more standard narrative with biographical details to make the subject come alive. With the media filled with talk of the discovery of genes 'for' an array of human behaviors, there has never been a more pressing need for today's students - tomorrow's researchers - to be equipped with a clear, balanced view of the field. How Genes Influence Behavior is the perfect guide for allstudents, delivered in the words of three researchers who have witnessed first-hand the emergence of this fascinating field, and whose own investigations have been central to our current understanding of it.Online Resource CentreThe Online Resource Centre to accompany How Genes Influence Behavior features the following resources for lecturers and students:For registered adopters:* Figures from the book, available to downloadFor students:* Hyperlinks to primary literature cited in the text

About The Author

Jonathan Flint is a Professor at the Wellcome Trust Centre for Human Genetics, Oxford University. He has extensive experience in molecular biology, molecular genetics, and rodent behavioural genetics with a specific focus on models of anxiety. Ralph Greenspan is based at the Neuroscience Institute in San Diego. He has studied the gene...

Details & Specs

Title:How Genes Influence BehaviorFormat:PaperbackDimensions:304 pages, 9.69 × 7.44 × 0.03 inPublished:February 1, 2010Publisher:Oxford University PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0199559902

ISBN - 13:9780199559909

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Table of Contents

1. Introduction2. Schizophrenia3. Molecular genetics - Linkage Analysis4. Alcohol, depression and sex5. Genetic association analysis and candidate genes6. Genome wide association studies7. Model systems: Mice8. Model systems: Genetic Variation in Flies and Worms9. Model Systems: Circadian Rhythms10. Model Systems: Neural Mechanisms of Learning and Memory11. E Pluribus Unum, Ex Uno Plura: Reconciling Single Gene and Multigene Pictures of Behavior12. Methods

Editorial Reviews

"I found this informative and brilliantly-written. I think students will enjoy learning from this resource which is current, engaging and witty. Two of the best researchers in the field have come together to share their most interesting and exciting career-stories." --Dr Alice Gregory, Goldsmiths, University of London