Autophagy in Mammalian Systems, Part B

Kobo ebook | March 5, 2009

Autophagy in Mammalian Systems, Part B
$185.59 online 
$232.00 list price save 20%

Prices and offers may vary in store

Available for download

Not available in stores

about

This is the companion volume to Daniel Klionsky’s Autophagy: Lower Eukaryotes, which features the basic methods in autophagy covering yeasts and alternative fungi (aspergillus, podospora, magnaporthe). Klionsky is one of the leading authorities in the field. He is the editor-in-chief of Autophagy. The November 2007 issue of Nature Reviews highlighted his article, “Autophagy: From phenomenology to molecular understanding in less than a decade. He is currently editing guidelines for the field, with 230 contributing authors, that will publish in Autophagy.

Particularly in times of stress, like starvation and disease, higher organisms have an internal mechanism in their cells for chewing up and recycling parts of themselves. The process of internal “house cleaning in the cell is called autophagy – literally self-eating. Breakthroughs in understanding the molecular basis of autophagy came after the cloning of ATG1 (autophagy-related gene 1) in yeast. (To date, 30 additional yeast genes have been identified.) These ATG genes in yeast were the stepping stones to the explosion of research into the molecular analysis of autophagy in higher eukaryotes. In the future, this research will help to design clinical approaches that can turn on autophagy and halt tumor growth.

Title:Autophagy in Mammalian Systems, Part BFormat:Kobo ebookPublished:March 5, 2009Publisher:Elsevier ScienceLanguage:English

The following ISBNs are associated with this title:

ISBN:9990057608636

Appropriate for ages: All ages

Look for similar items by category: