Human Cardiovascular Control

Hardcover | January 1, 1993

byLoring B. Rowell

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This is a new and comprehensive analysis of reflex and hormonal control of the human cardiovascular system that grew out of Rowell's 1986 volume, Human Circulation: Regulation During Physical Stress, and incorporates more recent findings. The goal is to assist students, physiologists andclinicians to understand control of pressure, vascular volume, and blood flow by examining the cardiovascular system during orthostasis and exercise, two stresses that most affect these variables. These stresses are employed to analyze the passive properties of the vascular system and provide abasis for a detailed examination of how these properties are modified by mechanical, neural, and humoral factors. Interactive effects of the vasculature on cardiac performance are stressed to underline the importance of autonomic control supplemented by muscle pumping to maintain adequateventricular filling pressure, particularly during exercise. Limitations in cardiac pumping ability, in oxygen diffusion from lungs to blood and from blood to active muscle, in metabolism, and in neural control of organ blood flow are analyzed to explain how total oxygen consumption is limited. Theunsolved mystery is the nature of signals that govern the cardiovascular responses to exercise. This is discussed in a new and critical synthesis of ideas and evidence concerning the specific "error signals" that are sensed and then corrected by activation of cardiac and vascular effectors duringexercise.

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From the Publisher

This is a new and comprehensive analysis of reflex and hormonal control of the human cardiovascular system that grew out of Rowell's 1986 volume, Human Circulation: Regulation During Physical Stress, and incorporates more recent findings. The goal is to assist students, physiologists andclinicians to understand control of pressure, va...

From the Jacket

This new analysis of reflex and hormonal control of the human cardiovascular system developed from questions raised in Human Circulation: During Physical Stress (Rowell, 1986) and from recent findings. The goal is to help students, physiologists and clinicians understand the control of pressure, vascular volume, and blood flow by exami...

Loring B. Rowell is a Professor of Physiology and Biophysics and of Medicine (Cardiology) at the University of Washington School of Medicine. Dr. Rowell has published over 150 research papers, chapters, and review articles and has served on the editorial boeards of American Journal of Physiology, Circulation Research, and the Journal ...
Format:HardcoverDimensions:520 pages, 6.38 × 9.49 × 1.42 inPublished:January 1, 1993Publisher:Oxford University Press

The following ISBNs are associated with this title:

ISBN - 10:0195073622

ISBN - 13:9780195073621

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Table of Contents

n 1Passive Effects of Gravity2. Reflex Control During Orthostasis3. Neural-Humoral Adjustments to Orthostasis and Long-Term Control4. Orthostatic Intolerance5. Central Circulatory Adjustments to Dynamic Exercise6. Control of Regional Blood Flow During Dynamic Exercise7. Control of Blood Flow to Dynamically Active Muscles8. Cardiovascular Adjustments to Isometric Contractions9. Limitations to Oxygen Uptake During Dynamic Exercise10. What Signals Govern the Cardiovascular Responses to Exercise? Role of Central Command11. What Signals Govern the Cardiovascular Responses to Exercise? Reflexes from Active Muscles12. Arterial Baroreflexes, Central Command, and Muscle Chemoreflexes: A Synthesis

Editorial Reviews

"This book provides a superb synthesis and compendium of what is known and not know-about cardiovascular function in people during exercise. Rowell gives excellent examples of integrative physiology in his description of the complex interplay or critical variables that maintaincardiopulmonary homeostasis during standing and dynamic exercise...Each chapter is well developed,informative, and provocative...Human Cardiovascular Control should be readily available to all cardiologists, cardiovascular physiologist, and those involved with exercise and sports who want tounderstand and be abreast of this discipline, It is an excellent and provocative textbook..." --Carl Rothe, Indiana University, School of Medicine