Human Genes And Genomes: Science, Health, Society

Paperback | October 30, 2017

byLeon E. Rosenberg, Diane Drobnis Rosenberg

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In the nearly 60 years since Watson and Crick proposed the double helical structure of DNA, the molecule of heredity, waves of discoveries have made genetics the most thrilling field in the sciences. The study of genes and genomics today explores all aspects of the life with relevance in the lab, in the doctor's office, in the courtroom and even in social relationships. In this helpful guidebook, one of the most respected and accomplished human geneticists of our time communicates the importance of genes and genomics studies in all aspects of life. With the use of core concepts and the integration of extensive references, this book provides students and professionals alike with the most in-depth view of the current state of the science and its relevance across disciplines. Bridges the gap between basic human genetic understanding and one of the most promising avenues for advances in the diagnosis, prevention and treatment of human disease. Includes the latest information on diagnostic testing, population screening, predicting disease susceptibility, pharmacogenomics and more Explores ethical, legal, regulatory and economic aspects of genomics in medicine. Integrates historical classical genetics approach with the latest discoveries in structural and functional genomics

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From the Publisher

In the nearly 60 years since Watson and Crick proposed the double helical structure of DNA, the molecule of heredity, waves of discoveries have made genetics the most thrilling field in the sciences. The study of genes and genomics today explores all aspects of the life with relevance in the lab, in the doctor's office, in the courtroo...

Since 1998, Leon E. Rosenberg has been a professor in the Department of Molecular Biology and the Woodrow Wilson School of Public and International Affairs at Princeton University. From 1991 to 1998, Rosenberg was Chief Scientific Officer of the Bristol-Myers Squibb Company.During Rosenberg's 26 year affiliation with Yale, he was the d...
Format:PaperbackDimensions:446 pages, 8.75 × 6.35 × 0.68 inPublished:October 30, 2017Publisher:Academic PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0128100931

ISBN - 13:9780128100936

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Table of Contents

Foreword
Framing the Field
Introducing the CORE CONCEPTS
Genetics
Growth, Development, and Reproduction
Transmission of Genes
Structure of Genes, Chromosomes, and Genomes
Expression of Genes and Genomes
Mutation
Biological Evolution
Human Individuality
Chromosome Abnormalities
Single-Gene Defects
Multifactorial Traits
Disorders of Variable Genomic Architecture
Birth Defects
The Genetics of Cancer
Detection and Treatment of Genetic Disorders
Population and Evolutionary Genetics
Personalized Genetics and Genomics
Glossary
Additional Reading
Answers to Review Questions