Human Papillomaviruses and Cervical Cancer: Biology and Immunology

Hardcover | August 1, 1994

EditorPeter L. Stern, Margaret A. Stanley

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Cervical cancer is a major disease worldwide, with 500,000 new cases diagnosed every year. Through aetiological studies, an association has been established with HPV infection throughout the pathological spectrum of this disease. A timely review of HPV infection in cervical cancer, this bookprovides the background to the potential for immunological intervention. Basic background is provided, ensuring the book's accessibility to all. Each chapter is integrated so that the book as a whole provides a detailed insight into the most relevant scientific issues of HPV and cervical cancer. This book will provide an interface for students, scientists andclinicians with a realistic and critical evaluation of the advances and problems in the implementation of immunologically based prophylactic and therapeutic strategies in HPV-associated disease.

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From the Publisher

Cervical cancer is a major disease worldwide, with 500,000 new cases diagnosed every year. Through aetiological studies, an association has been established with HPV infection throughout the pathological spectrum of this disease. A timely review of HPV infection in cervical cancer, this bookprovides the background to the potential for...

Peter L. Stern is at Christie Hospital, Manchester. Margaret A. Stanley is at University of Cambridge.

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Format:HardcoverDimensions:240 pages, 9.21 × 6.14 × 0.79 inPublished:August 1, 1994Publisher:Oxford University Press

The following ISBNs are associated with this title:

ISBN - 10:019854796X

ISBN - 13:9780198547969

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Table of Contents

1. The pathology of cervical intro-epithelial neoplasia carcinoma and human papilloma-virus infection2. Molecular genetics of human papilloma viruses3. Detection of human papilloma virus infections4. Epidemiology of HPV and cervical cancer5. Mechanisms of transformation by HPV6. Virus keratinocyte interactions in the infectious cycle7. Serological immune response to HPV8. the search for cell-mediated immunity to HPV: prospects for vaccine design9. MHC expression in the natural history of cervical cancer10. Towards vaccines against papilloma virus11. Immunological aspects of cutaneous warts12. Concluding remarks

Editorial Reviews

`This book is a timely review of HPV infection in cervical cancer and provides the background to the potential for immunological intervention.'Anticancer Research 15: (1995)