Human Virology

Paperback | June 8, 2016

byLeslie Collier, John Oxford, Paul Kellam

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Viruses are some of the simplest infectious agents on the planet, yet can cause severe and even life-threatening diseases in all forms of life - including humans. Despite relying on host cells in order to replicate, viruses can be capable of extremely rapid reproduction and very effectivetransmission from one person to another. Because of this, they have historically represented a significant proportion of the disease burden affecting humans, in addition to a number of new high profile diseases which have emerged in the last century. However, on a more positive note, the only twodiseases to have ever been eradicated by mankind were both viruses, giving hope that in the future more viruses can be eliminated.Human Virology provides a vivid introduction to this fascinating field, by incorporating both the molecular and clinical aspects of the subject. The general principles and properties of viruses are covered in the first part of the text, while part two provides a survey of the different virusfamilies and the human diseases they cause. Finally, the book concludes with some of the more practical aspects of the subject, such as immunization, antiviral chemotherapy and laboratory techniques.Throughout the text, case studies bring the subject to life by providing a unique perspective from real practicing doctors. In addition new "hot topic" boxes have been incorporated into this edition, featuring current important areas of research. Little prior knowledge is assumed, making HumanVirology the perfect text for those students new to the subject.The Online Resource Centre to accompany Human Virology features: For students: * multiple-choice questions for self-directed learning * Web links to online animations and videos For lecturers: * Figures from the book in electronic format, ready to download

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Viruses are some of the simplest infectious agents on the planet, yet can cause severe and even life-threatening diseases in all forms of life - including humans. Despite relying on host cells in order to replicate, viruses can be capable of extremely rapid reproduction and very effectivetransmission from one person to another. Because...

Leslie Collier was from 1978 to 1986 Professor of Virology at the London Hospital Medical College, being succeeded in this post by John Oxford. John Oxford is Professor of Virology at St. Bartholomew's and The Royal London School of Medicine and Dentistry at the University of London. He is the co-author of two standard texts on Influen...
Format:PaperbackDimensions:352 pagesPublished:June 8, 2016Publisher:Oxford University PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0198714688

ISBN - 13:9780198714682

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Table of Contents

Part 1: General principles1. Virology: how it all began and where it will go2. General properties of viruses3. Viral replication and genetics4. How viruses cause disease5. Resistance of the human body to virus infections6. Viruses and the community: the science and practice of epidemiologyPart 2: Specific virusesGroup 1 - Positive sense single stranded RNA viruses7. Picornaviruses: polio, hepatitis A, and common cold8. Astroviruses: gastroenteritis agents9. Calciviruses: norovirus and gastroenteritis10. Hepeviruses: hepatitis E11. Togaviruses: mosquito borne, Chikungunya, Rubella, and a teratogen12. Flaviviruses: mosquito borne, yellow fever, dengue, blood borne Hepatitis C13. Coronaviruses: respiratory MERS, SARSGroup 2 - Negative sense single stranded RNA viruses14. Myxoviruses: influenza A, B, C15. Arenaviruses: Lassa and haemorrhagic fevers16. Bunyaviruses: hanta, phlebo, and nairo viruses17. Paramyxoviruses: respiratory syncytial virus, meta pneumo virus and emerging Hendra and Nipah18. Filoviruses: zoonotic, Marburg, and Ebola19. Rabies: zoonotic rabiesGroup 3 - Double stranded RNA viruses20. Reoviruses: rota and diarrhoea virusesGroup 4 - Double stranded DNA viruses21. Polyomaviruses22. Papillomaviruses: warts and cervical carcinoma23. Herpes viruses: herpetic lesions, cancer, and encephalitis24. Smallpox: human disease eradicated but zoonotic infections common25. Adenovirus: respiratory, eye, and gastroenteritis virusesGroup 5 - Single stranded DNA viruses26. Parvovirus: childhood rash, aplastic crisis, foetal infectionGroup 6 - Single stranded positive sense RNA with an RT27. Retroviruses: HIV 1 and 2 and HTLVGroup 7 - Circular double stranded DNA viruses with an RT28. Hepadnaviruses: hepatitis B and DPart 3: Practical aspects29. The clinical virology laboratory: molecular techniques30. Control of viral disease by immunisation31. Antiviral chemotherapy